Cardiac arrhythmias

Patients with heart failure exhibit an increased ventilatory response to exercise; their slope of the overall ventilation/carbon dioxide production ratio (VE/VCO2) is elevated. This elevation is related to impaired exercise performance and is commonly explained by an increased ventilation—perfusion...

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Bibliographic Details
Published in:European heart journal 1996-05, Vol.17 (5), p.750-755
Main Authors: Andreas, S., Morguet, A. J., Werner, G. S., Kreuzer, H.
Format: Article
Language:English
Subjects:
congestive
exercise
Heart failure
ventilatory response
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Summary:Patients with heart failure exhibit an increased ventilatory response to exercise; their slope of the overall ventilation/carbon dioxide production ratio (VE/VCO2) is elevated. This elevation is related to impaired exercise performance and is commonly explained by an increased ventilation—perfusion mismatch. However, the concept of afferents to the respiratory centre modulating ventilation during exercise has been raised. In healthy subjects, ventilation during exercise is related to the hypercapnic ventilatory response during rebreathing. This is explained by a similar response of the respiratory centre to different stimuli. The aim of this study was to analyse the relationship between the ventilatory response to exercise and to carbon dioxide in patients with chronic heart failure. The hypercapnic ventilatory response was measured at rest using the rebreathing method in 31 patients with chronic heart failure and a left ventricular ejection fraction
ISSN:0195-668X
1522-9645
DOI:10.1093/oxfordjournals.eurheartj.a014942