Malignant lymphoma in the donor heart after heart transplantation

A case of post-transplant lymphoproliferative disease (PTLD) with donor heart involvement is reported. The 49-year-old patient presented with heart failure initially ascribed to acute graft rejection. The treatment with high doses of immunosuppressive agents was unsuccessful and the outcome rapidly...

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Bibliographic Details
Published in:European Heart Journal 1993, Vol.14 (8), p.1143-1145
Main Authors: BURTIN, P., GUERCI, A., BOMAN, F., DOPFF, C., PINELLI, G., HABERER, J. P., VILLEMOT, J. P.
Format: Report
Language:English
Subjects:
congestive heart failure
heart neoplasms
Heart transplantation
immunosuppression
immunosuppressive agents
non-Hodgkin lymphoma
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Summary:A case of post-transplant lymphoproliferative disease (PTLD) with donor heart involvement is reported. The 49-year-old patient presented with heart failure initially ascribed to acute graft rejection. The treatment with high doses of immunosuppressive agents was unsuccessful and the outcome rapidly fatal. This case suggests that cardiac failure occurring after high doses of immunosuppressive therapy could be a sign of early PTLD in heart transplant recipients.
ISSN:1522-9645
0195-668X
DOI:10.1093/eurheartj/14.8.1143