Validation of noninvasive assessment of coronary flow velocity reserve in the right coronary artery

Aims Assessment of coronary flow velocity reserve (CFR) noninvasively using transthoracic Doppler echocardiography (TDE) is validated for the left anterior descending artery only. We evaluated the feasibility and reproducibility to assess CFR using TDE in the right coronary artery, and compared the...

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Bibliographic Details
Published in:European heart journal 2003-09, Vol.24 (17), p.1567-1575
Main Authors: Lethen, Harald, Tries, Hans P., Kersting, Stefan, Lambertz, Heinz
Format: Article
Language:English
Subjects:
Coronary flow reserve
Echocardiography
Right coronary artery
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Summary:Aims Assessment of coronary flow velocity reserve (CFR) noninvasively using transthoracic Doppler echocardiography (TDE) is validated for the left anterior descending artery only. We evaluated the feasibility and reproducibility to assess CFR using TDE in the right coronary artery, and compared the results with intracoronary Doppler flow wire (DFW) measurements. Methods and results Introduction of a modified apical 2-chamber view allows visualization of the posterior descending branch of the right coronary artery (RPD). 42 consecutive patients (31 men, mean age 61±10) with suspected coronary artery disease scheduled for coronary angiography underwent CFR assessment using TDE in fundamental imaging mode; the results were compared with DFW measurements. CFR could be taken noninvasively in 81% (34/42); in case of right dominant- or balanced coronary circulation type success rate was significantly higher (87%; 33/38) than in case of left dominant coronary circulation (25%; 1/4). Correlation between echocardiographically and intracoronary derived CFR results was significant (r=0.85, P
ISSN:0195-668X
1522-9645
DOI:10.1016/S0195-668X(03)00284-7