Immunofluorescent Localization of Alpha1 Fetoprotein in Yolk Sac Carcinomas of the Rat

α1-Fetoprotein (AFP) was demonstrated by the immunofluorescent antibody staining technique in 1 primary and 3 transplantable yolk sac carcinomas of rats. AFP was observed only in structures with a characteristic endodermal appearance. This protein was not detected in embryonal carcinoma cells.

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1976-12, Vol.57 (6), p.1375-1377
Main Authors: Delacourt, M. C., Sobis, H., Vandeputte, M.
Format: Article
Language:English
Online Access:Get full text
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Description
Summary:α1-Fetoprotein (AFP) was demonstrated by the immunofluorescent antibody staining technique in 1 primary and 3 transplantable yolk sac carcinomas of rats. AFP was observed only in structures with a characteristic endodermal appearance. This protein was not detected in embryonal carcinoma cells.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/57.6.1375