DECREASED HELPER T LYMPHOCYTES IN HOMOSEXUAL MEN

In June 1982, sexual and other behavioral patterns were examined in 245 homosexual men in relationship to T-lymphocyte phenotypes that are character istic of the acquired Immunodeficiency syndrome (AIDS). Mean helper T-cell counts in New York City (579±32 cells/mm2 and Washington, DC, homosexual men...

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Bibliographic Details
Published in:American journal of epidemiology 1985-05, Vol.121 (5), p.629-636
Main Authors: GOEDERT, JAMES J., BIGGAR, ROBERT J., WINN, DEBORAH M., MANN, DEAN L., BYAR, DAVID P., STRONG, DOUGLAS M., DIGIOIA, RICHARD A., GROSSMAN, RONALD J., SANCHEZ, WILLIAM C., KASE, RONALD G., GREENE, MARK H., HOOVER, ROBERT N., BLATTNER, WILLIAM A.
Format: Article
Language:English
Subjects:
cellutar immunologic deficiency syndromes regres sion analysis
homosexuality
immunity
retrovlrus infections
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Summary:In June 1982, sexual and other behavioral patterns were examined in 245 homosexual men in relationship to T-lymphocyte phenotypes that are character istic of the acquired Immunodeficiency syndrome (AIDS). Mean helper T-cell counts in New York City (579±32 cells/mm2 and Washington, DC, homosexual men with sexual contacts In areas at high risk (endemic) for AIDS (567 ± 24 cells/mm3) were significantly lower than in Washington, DC, residents without such contacts (672 ± 36 cells/mm3, p = 0.04 by analysis of variance). Helper T cell counts in the Washington men were inversely correlated with a greater number of endemic-area homosexual contacts (p = 0.005), even after adjustment for multiple confounding variables (p = 0.02). The 31 Washington men with more than 15 endemic-area parthers had a mean helper T-cell count of 517 ± 44 cells/ mm3 and 12 of those 31 men had helper T-cell counts
ISSN:0002-9262
1476-6256
DOI:10.1093/aje/121.5.629