Rheumatoid Arthritis: Treatment [151–201]

Background: UK guidelines and a `Rheumatology' editorial suggest that liver function tests (LFTs) alone remain a satisfactory method for methotrexate (MTX) monitoring in rheumatoid arthritis (RA). Recent literature also suggests no difference in hepatotoxity between MTX treated RA and psoriatic...

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Published in:Rheumatology (Oxford, England) England), 2010-04, Vol.49 (suppl-1), p.i89-i111
Main Authors: Lloyd, Mark, Gwynne, Catherine, Lawson, Tom, Müller-Ladner, Ulf, Tyrrell, Helen, Loke, Yoon, MacGregor, Alex, Schiff, Michael, Domanska, Barbara, Morgan, Darrell, Langtree, Matthew, Lam, Manda, El Gaafary, Maha, Dutta, Shouma, Morcos, Peter N., Schmitt, Christophe, Isaacs, John D., Olech, Ewa, Deodhar, Atul, Keystone, Edward, Emery, Paul, Williams, Richard B., Rees, David H., Baird, Janis, Taylor, Peter C., Bracewell, Claire, Kidd, Elizabeth, Wright, David, Watson, Kathryn, Combe, Bernard, van der Heijde, Desiree, Stohl, William, Shaw, Tim, Keystone, Edward C., Smolen, Josef, Fleischmann, Roy M., Armstrong, Gillian K., Reynard, Mark, McInnes, Iain B., Codding, Christine, Songcharoen, Suthin, Berman, Alberto, Saldate, Cristina, Le Bars, Manuela, Burmester, Gerd R., Kary, Sonja, Patra, Kaushik, Kitas, George D., Genovese, Mark C., Hsia, Elizabeth C., Xu, Stephen, Curtis, Jeffery, Coteur, Geoffroy, Fleischmann, Roy, Goel, Niti, Desai, Chintu, Wang, Candace D., Curtis, Jeffrey R., Hughes, Lyndsay D., Young, Adam, Done, D. John, Bingham, Clifton O., Macey, Katherine, Russell, Anthony S., Abud-Mendoza, Carlos, Westhovens, Rene, Kavanaugh, Arthur, Sinisi, Sandra, Ansari, Zainab, Fraser, Owen, Tarelli, Edward, Breshnihan, Barry, Veale, Douglas J., Alasti, F., John, Ani K., John Done, D., Suzaki, Midori, Wordsworth, Paul, Landewe, Robert, Hsia, Elizabeth, Nishimoto, Norihiro, Kawata, Yuichi, Aoki, Chieko, Mima, Toru, Taylor, Andrew, Klareskog, Lars, Gomez-Reino, J. J.
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Language:English
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Summary:Background: UK guidelines and a `Rheumatology' editorial suggest that liver function tests (LFTs) alone remain a satisfactory method for methotrexate (MTX) monitoring in rheumatoid arthritis (RA). Recent literature also suggests no difference in hepatotoxity between MTX treated RA and psoriatic arthritis (PsA) patients. We describe 3 cases of liver fibrosis / cirrhosis missed by conventional monitoring. Methods: Case 1: 71 yr old female, RA 35 yrs. Presented 2005. Previous breast cancer. Alcohol
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/keq725