Loading…

functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition

Spatial and non-spatial sensory information is hypothesized to be evaluated in parallel pathways. In this study, we tested the spatial and non-spatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the non-spatial pathway. Activity was tested while...

Full description

Saved in:
Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2009-11, Vol.106 (47), p.20045-20050
Main Authors: Cohen, Y.E, Russ, B.E, Davis, S.J, Baker, A.E, Ackelson, A.L, Nitecki, R
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733
cites cdi_FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733
container_end_page 20050
container_issue 47
container_start_page 20045
container_title Proceedings of the National Academy of Sciences - PNAS
container_volume 106
creator Cohen, Y.E
Russ, B.E
Davis, S.J
Baker, A.E
Ackelson, A.L
Nitecki, R
description Spatial and non-spatial sensory information is hypothesized to be evaluated in parallel pathways. In this study, we tested the spatial and non-spatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the non-spatial pathway. Activity was tested while non-human primates reported changes in an auditory stimulus' spatial or non-spatial features. We found that vPFC neurons were reliably modulated during a non-spatial auditory task but were not modulated during a spatial auditory task. The degree of modulation during the non-spatial task correlated positively with the monkeys' behavioral performance. These results are consistent with the hypotheses that the vPFC is part of a circuit involved in non-spatial auditory processing and that the vPFC plays a functional role in non-spatial auditory cognition.
doi_str_mv 10.1073/pnas.0907248106
format article
fullrecord <record><control><sourceid>jstor_pnas_</sourceid><recordid>TN_cdi_jstor_primary_25593321</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>25593321</jstor_id><sourcerecordid>25593321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733</originalsourceid><addsrcrecordid>eNqFkU1v1DAQhiMEokvhzAmIOIA4pB1_xfYFCVV8SZU4QA-cLCdxtl5l7cV2KvrvmWhXXeAAJ9szz7yembeqnhI4IyDZ-S7YfAYaJOWKQHuvWhHQpGm5hvvVCoDKRnHKT6pHOW8AQAsFD6sTopWWkrJV9X2cQ198DHaqU5xcPcZUl2tX37hQMGCLS5jaJTemGApe-5iK-1n7UIcYmryzxWPUzoMvMd1ieh38Ivi4ejDaKbsnh_O0uvrw_tvFp-byy8fPF-8um14IUbBVGCkZZN9pGAhVUoBox1aMrRq4sp1USgMRru-YHajkbsBXZ9tBQddRydhp9Xavu5u7rRv6pW87mV3yW5tuTbTe_JkJ_tqs442hUgmqNAq8Pgik-GN2uZitz72bJhtcnLORjOMeKaNIvvonSQllmvIWwZd_gZs4J9wxMkCYbgkhCJ3voT7FnHHBdz0TMIu7ZnHXHN3Fiue_j3rkD3YiUB-ApfIo1xou8WfgApE3_0HMOE8TWlyQfbZnNxm9vYOpEJoxukzwYp8fbTR2nXw2V1-XAYFIUGgW-wVr5s05</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>201396111</pqid></control><display><type>article</type><title>functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition</title><source>PubMed (Medline)</source><source>JSTOR Archival Journals and Primary Sources Collection</source><creator>Cohen, Y.E ; Russ, B.E ; Davis, S.J ; Baker, A.E ; Ackelson, A.L ; Nitecki, R</creator><creatorcontrib>Cohen, Y.E ; Russ, B.E ; Davis, S.J ; Baker, A.E ; Ackelson, A.L ; Nitecki, R</creatorcontrib><description>Spatial and non-spatial sensory information is hypothesized to be evaluated in parallel pathways. In this study, we tested the spatial and non-spatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the non-spatial pathway. Activity was tested while non-human primates reported changes in an auditory stimulus' spatial or non-spatial features. We found that vPFC neurons were reliably modulated during a non-spatial auditory task but were not modulated during a spatial auditory task. The degree of modulation during the non-spatial task correlated positively with the monkeys' behavioral performance. These results are consistent with the hypotheses that the vPFC is part of a circuit involved in non-spatial auditory processing and that the vPFC plays a functional role in non-spatial auditory cognition.</description><identifier>ISSN: 0027-8424</identifier><identifier>EISSN: 1091-6490</identifier><identifier>DOI: 10.1073/pnas.0907248106</identifier><identifier>PMID: 19897723</identifier><language>eng</language><publisher>United States: National Academy of Sciences</publisher><subject>Acoustic Stimulation ; Animal cognition ; Animal vocalization ; Animals ; Auditory cortex ; Auditory Pathways - physiology ; Auditory Perception - physiology ; Auditory stimulation ; Behavior, Animal - physiology ; Behavioral neuroscience ; Biological Sciences ; Brain ; Cognition ; Cognition - physiology ; Correlation analysis ; Electrophysiology ; Geometric lines ; Humans ; Macaca mulatta ; Male ; Mental stimulation ; Monkeys &amp; apes ; Neurons ; Neurons - physiology ; Prefrontal cortex ; Prefrontal Cortex - anatomy &amp; histology ; Prefrontal Cortex - physiology ; Primates ; Psychomotor Performance - physiology ; Sensory perception ; Space Perception - physiology ; Studies ; Vocalization, Animal - physiology</subject><ispartof>Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.20045-20050</ispartof><rights>Copyright National Academy of Sciences Nov 24, 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733</citedby><cites>FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://www.pnas.org/content/106/47.cover.gif</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/25593321$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/25593321$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793,58238,58471</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19897723$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cohen, Y.E</creatorcontrib><creatorcontrib>Russ, B.E</creatorcontrib><creatorcontrib>Davis, S.J</creatorcontrib><creatorcontrib>Baker, A.E</creatorcontrib><creatorcontrib>Ackelson, A.L</creatorcontrib><creatorcontrib>Nitecki, R</creatorcontrib><title>functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition</title><title>Proceedings of the National Academy of Sciences - PNAS</title><addtitle>Proc Natl Acad Sci U S A</addtitle><description>Spatial and non-spatial sensory information is hypothesized to be evaluated in parallel pathways. In this study, we tested the spatial and non-spatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the non-spatial pathway. Activity was tested while non-human primates reported changes in an auditory stimulus' spatial or non-spatial features. We found that vPFC neurons were reliably modulated during a non-spatial auditory task but were not modulated during a spatial auditory task. The degree of modulation during the non-spatial task correlated positively with the monkeys' behavioral performance. These results are consistent with the hypotheses that the vPFC is part of a circuit involved in non-spatial auditory processing and that the vPFC plays a functional role in non-spatial auditory cognition.</description><subject>Acoustic Stimulation</subject><subject>Animal cognition</subject><subject>Animal vocalization</subject><subject>Animals</subject><subject>Auditory cortex</subject><subject>Auditory Pathways - physiology</subject><subject>Auditory Perception - physiology</subject><subject>Auditory stimulation</subject><subject>Behavior, Animal - physiology</subject><subject>Behavioral neuroscience</subject><subject>Biological Sciences</subject><subject>Brain</subject><subject>Cognition</subject><subject>Cognition - physiology</subject><subject>Correlation analysis</subject><subject>Electrophysiology</subject><subject>Geometric lines</subject><subject>Humans</subject><subject>Macaca mulatta</subject><subject>Male</subject><subject>Mental stimulation</subject><subject>Monkeys &amp; apes</subject><subject>Neurons</subject><subject>Neurons - physiology</subject><subject>Prefrontal cortex</subject><subject>Prefrontal Cortex - anatomy &amp; histology</subject><subject>Prefrontal Cortex - physiology</subject><subject>Primates</subject><subject>Psychomotor Performance - physiology</subject><subject>Sensory perception</subject><subject>Space Perception - physiology</subject><subject>Studies</subject><subject>Vocalization, Animal - physiology</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNqFkU1v1DAQhiMEokvhzAmIOIA4pB1_xfYFCVV8SZU4QA-cLCdxtl5l7cV2KvrvmWhXXeAAJ9szz7yembeqnhI4IyDZ-S7YfAYaJOWKQHuvWhHQpGm5hvvVCoDKRnHKT6pHOW8AQAsFD6sTopWWkrJV9X2cQ198DHaqU5xcPcZUl2tX37hQMGCLS5jaJTemGApe-5iK-1n7UIcYmryzxWPUzoMvMd1ieh38Ivi4ejDaKbsnh_O0uvrw_tvFp-byy8fPF-8um14IUbBVGCkZZN9pGAhVUoBox1aMrRq4sp1USgMRru-YHajkbsBXZ9tBQddRydhp9Xavu5u7rRv6pW87mV3yW5tuTbTe_JkJ_tqs442hUgmqNAq8Pgik-GN2uZitz72bJhtcnLORjOMeKaNIvvonSQllmvIWwZd_gZs4J9wxMkCYbgkhCJ3voT7FnHHBdz0TMIu7ZnHXHN3Fiue_j3rkD3YiUB-ApfIo1xou8WfgApE3_0HMOE8TWlyQfbZnNxm9vYOpEJoxukzwYp8fbTR2nXw2V1-XAYFIUGgW-wVr5s05</recordid><startdate>20091124</startdate><enddate>20091124</enddate><creator>Cohen, Y.E</creator><creator>Russ, B.E</creator><creator>Davis, S.J</creator><creator>Baker, A.E</creator><creator>Ackelson, A.L</creator><creator>Nitecki, R</creator><general>National Academy of Sciences</general><general>National Acad Sciences</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20091124</creationdate><title>functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition</title><author>Cohen, Y.E ; Russ, B.E ; Davis, S.J ; Baker, A.E ; Ackelson, A.L ; Nitecki, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Acoustic Stimulation</topic><topic>Animal cognition</topic><topic>Animal vocalization</topic><topic>Animals</topic><topic>Auditory cortex</topic><topic>Auditory Pathways - physiology</topic><topic>Auditory Perception - physiology</topic><topic>Auditory stimulation</topic><topic>Behavior, Animal - physiology</topic><topic>Behavioral neuroscience</topic><topic>Biological Sciences</topic><topic>Brain</topic><topic>Cognition</topic><topic>Cognition - physiology</topic><topic>Correlation analysis</topic><topic>Electrophysiology</topic><topic>Geometric lines</topic><topic>Humans</topic><topic>Macaca mulatta</topic><topic>Male</topic><topic>Mental stimulation</topic><topic>Monkeys &amp; apes</topic><topic>Neurons</topic><topic>Neurons - physiology</topic><topic>Prefrontal cortex</topic><topic>Prefrontal Cortex - anatomy &amp; histology</topic><topic>Prefrontal Cortex - physiology</topic><topic>Primates</topic><topic>Psychomotor Performance - physiology</topic><topic>Sensory perception</topic><topic>Space Perception - physiology</topic><topic>Studies</topic><topic>Vocalization, Animal - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cohen, Y.E</creatorcontrib><creatorcontrib>Russ, B.E</creatorcontrib><creatorcontrib>Davis, S.J</creatorcontrib><creatorcontrib>Baker, A.E</creatorcontrib><creatorcontrib>Ackelson, A.L</creatorcontrib><creatorcontrib>Nitecki, R</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cohen, Y.E</au><au>Russ, B.E</au><au>Davis, S.J</au><au>Baker, A.E</au><au>Ackelson, A.L</au><au>Nitecki, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>2009-11-24</date><risdate>2009</risdate><volume>106</volume><issue>47</issue><spage>20045</spage><epage>20050</epage><pages>20045-20050</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>Spatial and non-spatial sensory information is hypothesized to be evaluated in parallel pathways. In this study, we tested the spatial and non-spatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the non-spatial pathway. Activity was tested while non-human primates reported changes in an auditory stimulus' spatial or non-spatial features. We found that vPFC neurons were reliably modulated during a non-spatial auditory task but were not modulated during a spatial auditory task. The degree of modulation during the non-spatial task correlated positively with the monkeys' behavioral performance. These results are consistent with the hypotheses that the vPFC is part of a circuit involved in non-spatial auditory processing and that the vPFC plays a functional role in non-spatial auditory cognition.</abstract><cop>United States</cop><pub>National Academy of Sciences</pub><pmid>19897723</pmid><doi>10.1073/pnas.0907248106</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0027-8424
ispartof Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.20045-20050
issn 0027-8424
1091-6490
language eng
recordid cdi_jstor_primary_25593321
source PubMed (Medline); JSTOR Archival Journals and Primary Sources Collection
subjects Acoustic Stimulation
Animal cognition
Animal vocalization
Animals
Auditory cortex
Auditory Pathways - physiology
Auditory Perception - physiology
Auditory stimulation
Behavior, Animal - physiology
Behavioral neuroscience
Biological Sciences
Brain
Cognition
Cognition - physiology
Correlation analysis
Electrophysiology
Geometric lines
Humans
Macaca mulatta
Male
Mental stimulation
Monkeys & apes
Neurons
Neurons - physiology
Prefrontal cortex
Prefrontal Cortex - anatomy & histology
Prefrontal Cortex - physiology
Primates
Psychomotor Performance - physiology
Sensory perception
Space Perception - physiology
Studies
Vocalization, Animal - physiology
title functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T10%3A41%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_pnas_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=functional%20role%20for%20the%20ventrolateral%20prefrontal%20cortex%20in%20non-spatial%20auditory%20cognition&rft.jtitle=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20-%20PNAS&rft.au=Cohen,%20Y.E&rft.date=2009-11-24&rft.volume=106&rft.issue=47&rft.spage=20045&rft.epage=20050&rft.pages=20045-20050&rft.issn=0027-8424&rft.eissn=1091-6490&rft_id=info:doi/10.1073/pnas.0907248106&rft_dat=%3Cjstor_pnas_%3E25593321%3C/jstor_pnas_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c555t-640f21d7cb90d12875056f65f68d48ab7889015ecb3ad274ed015ba6d80bb2733%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=201396111&rft_id=info:pmid/19897723&rft_jstor_id=25593321&rfr_iscdi=true