Factors Associated with Participation in Providing Buccal Cell DNA for a Genetic Epidemiologic Study

Aims: Our aim was to investigate factors associated with participation in buccal cell DNA collection using a large-scale prospective cohort study. Methods: Of the 183,634 Korea Medical Insurance Corporation (KMIC) prospective cohort study enrollees, 44,773 (36,794 men) were randomly selected. Buccal...

Full description

Saved in:
Bibliographic Details
Published in:Community genetics 2011-01, Vol.14 (3), p.127-134
Main Authors: Kang, D.R., Kim, C., Hur, N.W., Shim, J.S., Shin, S.C., Suh, I.
Format: Article
Language:English
Subjects:
Adult
Blood Pressure
Body Mass Index
Cholesterol - blood
Deoxyribonucleic acid
DNA
DNA - genetics
Female
Genetics
Health Status Indicators
Humans
Life Style
Male
Middle Aged
Molecular Epidemiology
Mouth Mucosa - metabolism
Original Paper
Prospective Studies
Republic of Korea - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aims: Our aim was to investigate factors associated with participation in buccal cell DNA collection using a large-scale prospective cohort study. Methods: Of the 183,634 Korea Medical Insurance Corporation (KMIC) prospective cohort study enrollees, 44,773 (36,794 men) were randomly selected. Buccal cell collection kits were mailed and collected from March to September 2004. Epidemiologic characteristics measured at baseline (1990 or 1992) and during follow-up (1998) were compared between respondents and nonrespondents. Results: Among the 13,084 (29.2%) respondents, 78.7% submitted usable samples (DNA concentration ≧3 µg). After adjustments for either or both age and family history of chronic disease, participation in men was positively associated with old age, a family history of chronic disease, low subjective health status, and regular exercise, and negatively associated with current smoking status. In women, only old age was associated with participation. Low body mass index (BMI) (
ISSN:1662-4246
1662-8063
DOI:10.1159/000318808