Laboratory Management of Agents Associated with Hantavirus Pulmonary Syndrome: Interim Biosafety Guidelines

This report provides interim biosafety guidelines for preventing laboratory-associated infections with agents that cause hantavirus pulmonary syndrome. The guidelines are based on extensive laboratory experience with the other hantaviruses —particularly work involving the use of permissive host anim...

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Bibliographic Details
Published in:MMWR. Recommendations and reports 1994-05, Vol.43 (RR-7), p.i-7
Main Authors: Knudsen, Richard C., Mathews, Henry M., Richmond, Jonathan Y., Craven, Robert B., Garner, Julia S., Karabatsos, Nick, Khabbaz, Rima F., Ksiazek, Thomas G., Kuno, Goro, Mahy, Brian W.J., Peters, Clarence J., Rollin, Pierre E.
Format: Article
Language:English
Subjects:
Animals
Disease transmission
Hantavirus
Hantavirus pulmonary syndrome
Hemorrhagic fever with renal syndrome
Humans
Infections
Reverse transcriptase polymerase chain reaction
Rodents
Viruses
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Summary:This report provides interim biosafety guidelines for preventing laboratory-associated infections with agents that cause hantavirus pulmonary syndrome. The guidelines are based on extensive laboratory experience with the other hantaviruses —particularly work involving the use of permissive host animal species—and on the limited experience with a hantavirus recently isolated from deer mice. The guidelines address handling patient-derived specimens, propagating viruses in culture (including viral concentrate preparations), and housing and handling infected animals. These recommendations were developed with the assistance of expert consultants during a meeting of the American Society of Tropical Medicine and Hygiene, Subcommittee on Arbovirus Laboratory Safety, November 2, 1993, in Atlanta.
ISSN:1057-5987
1545-8601