Red Cell Antigen, Serum Protein and Red Cell Enzyme Polymorphisms in Eastern Highlanders of New Guinea

A series of 1,187 blood samples from eight population groups in the Eastern Highlands of Papua New Guinea were tested for genetic variation in blood groups, serum proteins and red cell enzyme systems. The populations belonged to the language groups Gahuku-Asarc-Bena Bena, Kamano, Yagaria, Keiagana,...

Full description

Saved in:
Bibliographic Details
Published in:Human heredity 1982-01, Vol.32 (6), p.374-384
Main Authors: Mourant, A. E., Tills, D., Homabrook, R. W., Warlow, A., Teesdale, P., Booth, P. B.
Format: Article
Language:English
Subjects:
Acid Phosphatase - genetics
Adenosine Deaminase - genetics
Blood Group Antigens - genetics
Blood Proteins - genetics
Erythrocytes - immunology
Humans
Isoenzymes - blood
Isoenzymes - genetics
Malate Dehydrogenase - genetics
Original Paper
Original Papers
Papua New Guinea
Phosphoglucomutase - genetics
Phosphogluconate Dehydrogenase - genetics
Polymorphism, Genetic
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A series of 1,187 blood samples from eight population groups in the Eastern Highlands of Papua New Guinea were tested for genetic variation in blood groups, serum proteins and red cell enzyme systems. The populations belonged to the language groups Gahuku-Asarc-Bena Bena, Kamano, Yagaria, Keiagana, Fore, Agarabe, Auyana and Tairora. Polymorphic variation was found in the ABO, MNS, P₁, Rh, Hp, Tf, SEP, 6-PGD, ADA, MDH, and PGM genetic systems. East to West variation was shown in the language groups; the O, S, R₂, and R₀ genes increase in frequency from East to West and the A, R₁, and M genes decrease in the same direction. In the East higher frequencies were found for the Du antigen, for the PGM²₁ gene and for a PGM second locus variant. The MDH 3 variant was found in all the populations, its highest value being in the Tairora.
ISSN:0001-5652
1423-0062
DOI:10.1159/000153327