Protein Changes in Different Brain Areas as a Function of Intermittent Training

Incorporation of [3H]leucine into protein of eight different brain areas in rats was determined during 1 month of intermittent training for reversal of handedness. The incorporation values of all areas of the trained animals were lower than those of the controls. This finding was corroborated by aut...

Full description

Saved in:
Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1972-07, Vol.69 (7), p.1980-1984
Main Authors: Hyden, Holger, Lange, Paul W.
Format: Article
Language:English
Subjects:
Animals
Autoradiography
Behavior, Animal
Biological Sciences: Psychology
Brain - metabolism
Cerebral Cortex - cytology
Cerebral Cortex - metabolism
Entorhinal cortex
Female
Functional Laterality
Hippocampus
Hippocampus - cytology
Hippocampus - metabolism
Hypothalamus - metabolism
Intraperitoneal injections
Learning
Leucine - metabolism
Limbic system
Limbic System - metabolism
Mathematics
Nerve Tissue Proteins - metabolism
Neurons
Proteins
Pyramidal cells
Rats
Reticular formation
Septum
Thalamus - metabolism
Time Factors
Tritium
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Incorporation of [3H]leucine into protein of eight different brain areas in rats was determined during 1 month of intermittent training for reversal of handedness. The incorporation values of all areas of the trained animals were lower than those of the controls. This finding was corroborated by autoradiography. After initial training the relative specific activities of the sensory-motor and entorhinal cortex and reticular formation were low compared to those of the hippocampus. With more training and time, these values became inversed.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.69.7.1980