Immunoglobulin Allotypes of European Populations

The distribution of Glm(f, z, a, and x), G3m(b0, b1, b3, c3, c5, g, s, and t) and Km(1) (formerly Inv[1]) allotypic markers have been examined in 184 Hungarians. The results indicate that the frequency of the immunoglobulin haplotypes Gm za;g , Gm zax;g , Gm f;b and Km 1 is similar to the frequencie...

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Bibliographic Details
Published in:Human heredity 2008-08, Vol.25 (5), p.370-377
Main Authors: Schanfield, M.S., Gergely, J., Fudenberg, H.H.
Format: Article
Language:English
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Summary:The distribution of Glm(f, z, a, and x), G3m(b0, b1, b3, c3, c5, g, s, and t) and Km(1) (formerly Inv[1]) allotypic markers have been examined in 184 Hungarians. The results indicate that the frequency of the immunoglobulin haplotypes Gm za;g , Gm zax;g , Gm f;b and Km 1 is similar to the frequencies observed in surrounding populations. In addition, Hungarians were found to be polymorphic for the Oriental haplotype Gm za;bst , and had low frequencies of other uncommon haplotypes. Our data indicate that about 5% of the Hungarian genome is of Oriental origin.
ISSN:0001-5652
1423-0062
DOI:10.1159/000152748