IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation

Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lympha...

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Bibliographic Details
Published in:Case reports in oncology 2020-01, Vol.13 (1), p.462-467
Main Authors: Yoshida, Saaya, Fujimura, Taku, Ohuchi, Kentaro, Kambayashi, Yumi, Segawa, Yuichiro, Yamazaki, Emi, Tono, Hisayuki, Takahashi, Toshiya, Tsuchiyama, Kenichiro, Aiba, Setsuya
Format: Article
Language:English
Subjects:
Angiogenesis
angiosarcoma
Cancer therapies
Case Report
Case reports
Cell growth
Cervical cancer
Collagen
Cytokines
Edema
Genital cancers
il-17
il-23
Metastasis
Neutrophils
Outpatient care facilities
Penis
Purpura
R&D
Radiation therapy
Research & development
Skin cancer
stewart-treves syndrome
Tumorigenesis
Tumors
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Summary:Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17.
ISSN:1662-6575
1662-6575
DOI:10.1159/000506975