Secondary Renal Amyloidosis in Adult Onset Still`s Disease : Case report and Review of the Literature

We report a 25-year-old Korean woman with Adult onset Still`s disease (AOSD) presented with renal amyloidosis, which had developed four years after disease onset. We successfully treated her with prednisolone, colchicine and cyclophosphamide. A review of the literature uncovered about 10 cases, most...

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Bibliographic Details
Published in:The Korean journal of internal medicine 2000-07, Vol.15 (2), p.131
Main Authors: Young Bae Oh, Sang Cheol Bae, Ja Hun Jung, Tae Hwan Kim, Jae Bum Jun, Sung Soo Jung, In Hong Lee, Dae Hyun Yoo, Moon Hyang Park, Seong Yoon Kim
Format: Article
Language:Korean
Subjects:
Genotype
HCV RNA replication
hepatitis C virus
Immune Response
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Summary:We report a 25-year-old Korean woman with Adult onset Still`s disease (AOSD) presented with renal amyloidosis, which had developed four years after disease onset. We successfully treated her with prednisolone, colchicine and cyclophosphamide. A review of the literature uncovered about 10 cases, most of which were treated by various regimens that resulted in poor outcomes. Renal amyloidosis should be suspected in patients with AOSD who have unexplained proteinuria. Although the mechanism of renal amyloid deposition is not well known, earlier histopathologic diagnosis and choice of regimen may affect prognosis.
ISSN:1226-3303
2005-6648