Long-Term Treatment Efficacy and Safety of Clevudine Therapy in Na?ve Patients with Chronic Hepatitis B

Background/Aims: Clevudine (CLV) has potent antiviral activity against chronic hepatitis B (CHB) virus infection. The long-term efficacy and safety of CLV therapy in na?ve patients with CHB were investigated. Methods: In this retrospective study, 152 na?ve Korean patients with CHB who received 30 mg...

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Bibliographic Details
Published in:Gut and liver 2012-10, Vol.6 (4), p.486
Main Authors: Bum Su Choung, In Hee Kim, Byung Jun Jeon, Seok Lee, Seong Hun Kim, Sang Wook Kim, Seung Ok Lee, Soo Teik Lee, Dae Ghon Kim
Format: Article
Language:Korean
Subjects:
2`-Fluoro-5-methylarabinosyl-uracil
Chronic hepatitis B
Muscular diseases
Viral breakthrough
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Summary:Background/Aims: Clevudine (CLV) has potent antiviral activity against chronic hepatitis B (CHB) virus infection. The long-term efficacy and safety of CLV therapy in na?ve patients with CHB were investigated. Methods: In this retrospective study, 152 na?ve Korean patients with CHB who received 30 mg of CLV once daily for at least 12 months were investigated. Results: The cumulative rates at months 12, 24, and 36, respectively, were 65.8%, 74.7%, and 74.7% for undetectable serum hepatitis B virus (HBV) DNA (
ISSN:1976-2283