혈청양성 류마티스관절염 환자에서 급성 신부전을 동반한 다발성 골수종

It is known that rheumatoid arthritis (RA) patients show increased incidence of multiple myeloma (MM), despite its rarity. Only one case of MM with seronegative RA was reported in Korea, thus far. We report a case of MM with seropositive RA. The patient was a 66 year old female who had been diagnose...

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Bibliographic Details
Published in:Journal of rheumatic diseases 2014-10, Vol.21 (5), p.266
Main Authors: 이승경, Seung Kyung Lee, 황선혁, Sun Hyuk Hwang, 박주한, Joo Han Park, 송가원, Ga Won Song, 박선영, Sun Young Park, 김세란, Sei Rhan Kim, 정주양, Ju Yang Jung, 배창범, Chang Bum Bae, 김현아, Hyoun Ah Kim, 정성현, Seong Hyun Jeong, 임현이, Hyun Ee
Format: Article
Language:Korean
Subjects:
Acute renal failure
Multiple myeloma
Proteinuria
Rheumatoid arthritis
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Summary:It is known that rheumatoid arthritis (RA) patients show increased incidence of multiple myeloma (MM), despite its rarity. Only one case of MM with seronegative RA was reported in Korea, thus far. We report a case of MM with seropositive RA. The patient was a 66 year old female who had been diagnosed with seropositive RA 4 years ago. Over the last 1 month, the patient experienced general weakness and weight loss of 10 kg. It was found that her serum creatinine had increased and her urine analysis showed proteinuria. To evaluate renal failure and proteinuria, renal biopsy, bone marrow biopsy and electrophoresis were carried out. A diagnosis of myeloma cast nephropathy was made. We report this rare case of MM represented as acute renal failure during the treatment for RA, and include a review of the literature.
ISSN:2093-940X