CASE REPORT : Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia

Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids....

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Bibliographic Details
Published in:Tuberculosis and respiratory diseases 2015-10, Vol.78 (4), p.401
Main Authors: Ji Hyun Oh, Dong Jun Oh, So My Koo, Yang Ki Kim, Ki Up Kim, Hyun Jo Kim, Dong Won Kim, Soo Taek Uh
Format: Article
Language:Korean
Subjects:
Adrenal Cortex Hormones
Clarithromycin
Cryptogenic Organizing Pneumonia
Macrolides
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Summary:Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids. A few reports showed treatment failure with macrolides in patients with COP who were resistant to steroids. In this report, we described two cases of COP who showed different responses to clarithromycin. One recovered completely, but the other gradually showed lung fibrosis with clarithromycin.
ISSN:1738-3536
2005-6184