Relationship between serum IgA level and allergy/ asthma

Background/Aims: Mucosal immunoglobulin A (IgA) may prevent the entrance of allergens. This study examined the relationship between serum IgA levels (within the normal range) and sensitization to house dust mites (HDM) or airway hyper-responsiveness (AHR). Methods: The clinical records of 1,136 adul...

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Bibliographic Details
Published in:The Korean journal of internal medicine 2017-01, Vol.32 (1), p.137
Main Authors: Woo-jin Kim, Inseon S. Choi, Chang Seong Kim, Jeong-hyeon Lee, Hyeon-wook Kang
Format: Article
Language:Korean
Subjects:
Asthma
Hyper-responsiveness
Immunoglobulin A
Sensitization
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Summary:Background/Aims: Mucosal immunoglobulin A (IgA) may prevent the entrance of allergens. This study examined the relationship between serum IgA levels (within the normal range) and sensitization to house dust mites (HDM) or airway hyper-responsiveness (AHR). Methods: The clinical records of 1,136 adult patients with suspected asthma, for whom test data for serum IgA level and methacholine-AHR were available, were reviewed retrospectively. The AHR/allergy indices were compared among patient groups with low (
ISSN:1226-3303
2005-6648