Quality of Life after Endoscopic Submucosal Dissection for Early Gastric Cancer: A Prospective Multicenter Cohort Study

Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC....

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Published in:Gut and liver 2017-01, Vol.11 (1), p.87
Main Authors: Sang Gyun Kim, Seon Mi Ji, Na Rae Lee, Seung-hee Park, Ji Hye You, Il Ju Choi, Wan Sik Lee, Seun Ja Park, Jun Haeng Lee, Sang-yong Seol, Ji Hyun Kim, Chul-hyun Lim, Joo Young Cho, Gwang Ha
Format: Article
Language:Korean
Subjects:
Early gastric cancer
Endoscopic submucosal dissection
Quality of life
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Summary:Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire- core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p
ISSN:1976-2283