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Differences in Abdominal Body Composition According to Glycemic Status: An Inverse Probability Treatment Weighting Analysis

Background: Several studies have reported that abdominal fat and muscle changes occur in diabetic patients. However, there are few studies about such changes among prediabetic patients. In this study, we evaluated the differences in abdominal fat and muscles based on abdominopelvic computed tomograp...

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Published in:Endocrinology and metabolism (Seoul) 2021-08, Vol.36 (4), p.855
Main Authors: Seungbong Han, Young-jee Jeon, Gyung-min Park, Tae Young Lee, Soon Eun Park, Gyeongseok Yu, Byung Ju Kang
Format: Article
Language:Korean
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Summary:Background: Several studies have reported that abdominal fat and muscle changes occur in diabetic patients. However, there are few studies about such changes among prediabetic patients. In this study, we evaluated the differences in abdominal fat and muscles based on abdominopelvic computed tomography in prediabetic and diabetic subjects compared to normal subjects. Methods: We performed a cross-sectional study using health examination data from March 2014 to June 2019 at Ulsan University Hospital and classified subjects into normal, prediabetic, and diabetic groups. We analyzed the body mass index corrected area of intra-abdominal components among the three groups using inverse probability treatment weighting (IPTW) analysis. Results: Overall, 8,030 subjects were enrolled; 5,137 (64.0%), 2,364 (29.4%), and 529 (6.6%) subjects were included in the normal, prediabetic, and diabetic groups, respectively. After IPTW adjustment of baseline characteristics, there were significant differences in log visceral adipose tissue index (VATI; 1.220.64 ㎠/[kg/㎡] vs. 1.300.63 ㎠/[kg/㎡] vs. 1.470.64 ㎠/[kg/㎡], P
ISSN:2093-596X