Partial cross-resistance between Strongyloides venezuelensis and Nippostrongylus brasiliensis in rats

Rats were immunized through an initial infection with 1,000 filariform larvae (L3) of Nippostrongylus brasiliensis and after complete expulsion of worms they were challenged with 1,000 L3 of Strongyloides venezuelensis to investigate whether cross-resistance developed against a heterologous parasite...

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Bibliographic Details
Published in:Korean journal of parasitology 1999, Vol.37 (2), p.101-107
Main Authors: Baek, Byeong-Kirl, Islam, M.-Khyrul, Kim, Jin-Ho, Lee, John-Wha, Hur, Jin
Format: Article
Language:Korean
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Summary:Rats were immunized through an initial infection with 1,000 filariform larvae (L3) of Nippostrongylus brasiliensis and after complete expulsion of worms they were challenged with 1,000 L3 of Strongyloides venezuelensis to investigate whether cross-resistance developed against a heterologous parasite. Nippostrongylus brasiliensis immunized rats developed a partial cross-resistance against S.venezuelensis migrating larvae (MSL3) in the lungs and adult worms in the small intestine. The population of MSL3 in the lungs were significantly lower (p
ISSN:0023-4001
1738-0006