Norisoprenoids and Hepatoprotective Flavone Glycosides from the Aerial Parts of Beta vulgaris var. cicla

(＋）-Dehydrovomifoliol (1）. 3-hydroxy-5$\alpha$,6$\alpha$-epoxy-$\beta$-ionone (2）, vitexin 7 -O-$\beta$-D-glucopyrano-side (3）, and vitexin 2'-O-$\beta$-D-glucopyranoside (4） were isolated as new constituents from the aerial parts of Beta vulgaris var. cicla. Compounds 3 and 4 demonstrated hepa...

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Bibliographic Details
Published in:Archives of pharmacal research 2004, Vol.27 (6), p.600-603
Main Authors: Kim, In-Kyum, Chin, Young-Won, Lim, Song-Won, Kim, Young-Choong, Kim, Jin-Woong
Format: Article
Language:Korean
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Summary:(＋）-Dehydrovomifoliol (1）. 3-hydroxy-5$\alpha$,6$\alpha$-epoxy-$\beta$-ionone (2）, vitexin 7 -O-$\beta$-D-glucopyrano-side (3）, and vitexin 2'-O-$\beta$-D-glucopyranoside (4） were isolated as new constituents from the aerial parts of Beta vulgaris var. cicla. Compounds 3 and 4 demonstrated hepatoprotective activity with values of 65.8 and 56.1％, respectively, in primary cultured rat hepatocytes with $CCl_4$-induced cell toxicity, compared to controls. This was comparable to that of silibinin (69.8％） which was used as a positive control.trol.
ISSN:0253-6269
1976-3786