Microwave Assisted N-Alkenyl Condensation between Pyrrolidine-2-thione and Various Aldehydes

A series of N-alkenyl pyrrolidine-2-thiones were synthesized by the reaction between pyrrolidine-2-thione and various aldehydes such as n-propanal, isopropanal, n-butanal, n-hexanal, n-octanal and phenylacetaldehyde in 32-86% yields using microwave irradiation technique. Only one structural E isomer...

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Bibliographic Details
Published in:Bulletin of the Korean Chemical Society 2008, Vol.29 (3), p.604-608
Main Authors: Kim, Ki-Won, Lee, Ho-Joon, Kim, Chung-Gi, Park, Mi-Ja, Kwon, Tae-Woo
Format: Article
Language:Korean
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Summary:A series of N-alkenyl pyrrolidine-2-thiones were synthesized by the reaction between pyrrolidine-2-thione and various aldehydes such as n-propanal, isopropanal, n-butanal, n-hexanal, n-octanal and phenylacetaldehyde in 32-86% yields using microwave irradiation technique. Only one structural E isomers were predominantly formed within 15 minutes in chlorobenezene?/p-toluenesulfonic acid monohydrate.
ISSN:0253-2964
1229-5949