오가피(Acanthopanax sessiliflorus Seeman) 열매로부터 분리한 페놀 화합물의 항산화활성

The fruits of Acanthopanax sessiliflorus Seeman (Araliaceae) were extracted with 70% aqueous ethanol at room temperature. The concentrated extract was partitioned with ethyl acetate (EtOAc), n-butyl alcohol, and H2O, successively. From the EtOAc fraction, two compounds were isolated through the repe...

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Bibliographic Details
Published in:Journal of applied biological chemistry 2012-12, Vol.55 (4), p.217-220
Main Authors: 인서지, Seo Ji In, 이대영, Dae Young Lee, 서경화, Kyeong Hwa Seo, 남태규, Tae Gyu Nam, 김대옥, Dae Ok Kim, 김금숙, Geum Soog Kim, 노형준, Hyung Jun Noh, 김계원, Gye Won Kim, 서우덕, Woo Duck Seo, 강희철, Hee Cheol Kang, 백남인, Nam In Baek
Format: Article
Language:Korean
Subjects:
1
1-diphenyl-2-picrylhydrazyl NMR
2
2`-azino-bisdiammonium salt
3
5-dihydroxycinnamic acid
Acanthopanax sessiliflorus
oxygen radical absorbance capacity
protocatechuic acid
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Summary:The fruits of Acanthopanax sessiliflorus Seeman (Araliaceae) were extracted with 70% aqueous ethanol at room temperature. The concentrated extract was partitioned with ethyl acetate (EtOAc), n-butyl alcohol, and H2O, successively. From the EtOAc fraction, two compounds were isolated through the repeated silica gel, octadecyl silica gel, and Sephadex LH-20 column chromatographies. According to the results of physicochemical and spectroscopic data including NMR, mass spectrometry, and infrared spectroscopy, the chemical structures of the compounds were determined as 3,5-dihydroxycinnamic acid (1) and protocatechuic acid (2). Compound 1 was isolated from the fruits of A. sessiliflirus Seeman for the first time. And the compounds were evaluated for the radical scavenging the antioxidant capacity using 2,2`-azino-bis(3-ethylbenzthiazoline-6- sulfonic acid)diammonium salt, 1,1-diphenyl-2-picrylhydrazy, and oxygen radical absorbance capacity assay.
ISSN:1976-0442
2234-7941