A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis

Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic p...

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Bibliographic Details
Published in:Tuberculosis and respiratory diseases 2012-08, Vol.73 (2), p.115-121
Main Authors: Park, Ki Hoon, Kwon, Soon Seog, Chung, Myung Hee, Kim, Jeana, Lee, Hee Jung, Min, Ji-Won, Kim, Yong Hyun
Format: Article
Language:Korean
Subjects:
Interstitial
Lymphoid Tissue
Lymphoma
Lymphoproliferative Disorders
Lung Diseases
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Summary:Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic pulmonary lymphoproliferative disorder, such as lymphocytic interstitial pneumonitis (LIP). A recent estimate predicts that less than 5% of LIP patients acquire malignant, low-grade, B-cell lymphoma. In Korea, there has been no previous report of malignant low-grade, B-cell lymphoma, acquired from LIP. Here, we present the case of a patient with LIP that developed into pulmonary MALT lymphoma, six years after diagnosis.
ISSN:1738-3536
2005-6184