Ischemia Modified Albumin Levels and Oxidative Stress in Patients with Bladder Cancer

Background: Impaired oxidative/antioxidative status plays an important role in the pathogenesis of many diseases like cancer. The aim of this study was to evaluate the levels of the novel marker ischemia modified albumin (IMA) and albumin adjusted-IMA (Adj-IMA) in patients with bladder cancer (BC) a...

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Bibliographic Details
Published in:Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 (5), p.2759-2763
Main Authors: Ellidag, Hamit Yasar, Eren, Esin, Aydin, Ozgur, Akgol, Evren, Yalcinkaya, Soner, Sezer, Cem, Yilmaz, Necat
Format: Article
Language:Korean
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Summary:Background: Impaired oxidative/antioxidative status plays an important role in the pathogenesis of many diseases like cancer. The aim of this study was to evaluate the levels of the novel marker ischemia modified albumin (IMA) and albumin adjusted-IMA (Adj-IMA) in patients with bladder cancer (BC) as well as its association with total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI). Materials and Methods: Forty male patients with BC (mean age, $67.4{\pm}12$ years) and forty age-sex matched healthy persons (mean age $56.0{\pm}1.7$ years) were included in this study. Serum levels of IMA, TAS, TOS were analyzed and Adj- IMA and OSI was calculated. Results: Serum IMA, TOS and OSI values were significantly higher in patients with BC compared to controls (p
ISSN:1513-7368
2476-762X