Reproductive technologies needed for the generation of precise gene-edited pigs in the pathways from laboratory to farm

Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic...

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Bibliographic Details
Published in:Animal bioscience 2023, Vol.36 (2), p.339-349
Main Authors: Ching-Fu Tu, Shu-Hui Peng, Chin-kai Chuang, Chi-Hong Wong, Tien-Shuh Yang
Format: Article
Language:Korean
Online Access:Get full text
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Summary:Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic cell nuclear transfer, cryopreservation, and nonsurgical embryo transfer. The extension of NBT in the new era of pig breeding depends on the synergistic effect of GE and reproductive biotechnologies; the outcome relies not only on scientific due diligence and operational excellence but also on the feasibility of application on farms to improve sustainability.
ISSN:2765-0189
2765-0235