Sequencing antibody repertoires: The next generation

Genomic studies have been revolutionized by the use of next generation sequencing (NGS) that delivers huge amounts of sequence information in a short span of time. The number of applications for NGS is rapidly expanding and significantly transforming many areas of life sciences. The field of antibod...

Full description

Saved in:
Bibliographic Details
Published in:mAbs 2011-01, Vol.3 (1), p.17-20
Main Author: Fischer, Nicolas
Format: Article
Language:English
Subjects:
Antibodies - genetics
Binding
Biology
Bioscience
Calcium
Cancer
Cell
Cycle
Gene Library
Genomics
Humans
Landes
Organogenesis
Peptide Library
Proteins
Quality Control
Sequence Analysis, DNA - methods
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Genomic studies have been revolutionized by the use of next generation sequencing (NGS) that delivers huge amounts of sequence information in a short span of time. The number of applications for NGS is rapidly expanding and significantly transforming many areas of life sciences. The field of antibody research and discovery is no exception. Several recent studies have harnessed the power of NGS for analyzing natural or synthetic immunoglobulin repertoires with unprecedented resolution and exploring alternative paths for antibody discovery. Thus, appreciating, and then exploiting, these advances is essential for staying at the edge of antibody innovation.
ISSN:1942-0862
1942-0870
DOI:10.4161/mabs.3.1.14169