Stronger Suppression of Serum Testosterone and FSH Levels by a Synthetic Estrogen than by Castration or an LH-RH Agonist

Serum levels of LH, FSH and testosterone(T)were measured by radioimmunoassays in 36 patients with advanced prostate cancer before and during androgen ablation therapies. Both leuprolide acetate(LH-RH agonist：LHRH-A)and diethylstilbestrol diphosphate(DES-DP)administration decreased serum LH significa...

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Published in:ENDOCRINE JOURNAL 1997, Vol.44 (4), p.527-532
Main Authors: SATOSHI KITAHARA, KEN-ICHIRO YOSHIDA, KAZUHIRO ISHIZAKA, YUKIO KAGEYAMA, SATORU KAWAKAMI, TOSHIHIKO TSUJII, HIROYUKI OSHIMA
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Language:Japanese
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Summary:Serum levels of LH, FSH and testosterone(T)were measured by radioimmunoassays in 36 patients with advanced prostate cancer before and during androgen ablation therapies. Both leuprolide acetate(LH-RH agonist：LHRH-A)and diethylstilbestrol diphosphate(DES-DP)administration decreased serum LH significantly to an undetectable level(LHRH-A：P
ISSN:0918-8959