An Increase in Serum Retinol-Binding Protein 4 in the Type 2 Diabetic Subjects with Nephropathy

Abstract. The present study was undertaken to determine retinol-binding protein 4 (RBP4) levels in subjects with diabetic nephropathy. A total of 149 type 2 diabetic subjects and 19 control subjects were enrolled. Serum levels of RBP4 were measured by a method of ELISA. Serum RBP4 levels were signif...

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Published in:ENDOCRINE JOURNAL 2009, Vol.56 (2), p.287-293
Main Authors: MIHO MURATA, TOMOYUKI SAITO, TAEKO OTANI, MASAMI SASAKI, AKI IKOMA, HIDEO TOYOSHIMA, MASANOBU KAWAKAMI, SAN-E ISHIKAWA
Format: Article
Language:Japanese
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Summary:Abstract. The present study was undertaken to determine retinol-binding protein 4 (RBP4) levels in subjects with diabetic nephropathy. A total of 149 type 2 diabetic subjects and 19 control subjects were enrolled. Serum levels of RBP4 were measured by a method of ELISA. Serum RBP4 levels were significantly greater in the subjects with type 2 diabetes mellitus than the controls (70.5±35.3 vs. 40.1±13.0μg/ml, mean±SD, p
ISSN:0918-8959