Three cases of diffuse panbronchiolitis in children with a past history of difficult-to-treat bronchial asthma : A case report from a single medical facility

Dear Editor, Diffuse panbronchiolitis (DPB) is a chronic inflammatory lung disease frequently complicated with chronic sinusitis, causing cough, sputum and respiratory distress. The Ministry of Health and Welfare of Japan (MHLW) proposes the definite diagnosis of DPB as having all of the 3 major cri...

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Bibliographic Details
Published in:Allergology International 2020-07, Vol.69 (3), p.468-470
Main Authors: Satoshi Fujitaa, b, Ryohei Suzukia, Nagatoshi Sagaraa, Akiko Aotaa, Kenichi Akashia, Toshio Katsunumaa
Format: Article
Language:Japanese
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Summary:Dear Editor, Diffuse panbronchiolitis (DPB) is a chronic inflammatory lung disease frequently complicated with chronic sinusitis, causing cough, sputum and respiratory distress. The Ministry of Health and Welfare of Japan (MHLW) proposes the definite diagnosis of DPB as having all of the 3 major criteria (1. persistent cough, sputum, and exertional dyspnea, 2. past history of recurrent chronic sinusitis, 3. bilateral diffuse small nodular shadows on plain chest X-ray film or centrilobular nodular shadows on chest CT images) and at least 2 of the 3 minor criteria (1. coarse crackles, 2. forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) less than 70% and PaO2 less than 80 mmHg, 3. titre of cold agglutinin equal to or higher than 64). DPB in children are rare and some cases are firstly diagnosed as difficult-to-treat bronchial asthma.
ISSN:1323-8930