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Managing anthelmintic resistance: Modelling strategic use of a new anthelmintic class to slow the development of resistance to existing classes

AIM: To test the hypothesis that a single strategic treatment with a new class of anthelmintic could slow the development of resistance to existing classes of anthelmintic. METHODS: An existing model was used to simulate nematode parasite dynamics and the development of anthelmintic resistance. Vari...

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Bibliographic Details
Published in:New Zealand veterinary journal 2009-08, Vol.57 (4), p.203-207
Main Authors: Leathwick, DM, Hosking, BC
Format: Article
Language:English
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Summary:AIM: To test the hypothesis that a single strategic treatment with a new class of anthelmintic could slow the development of resistance to existing classes of anthelmintic. METHODS: An existing model was used to simulate nematode parasite dynamics and the development of anthelmintic resistance. Variations on a five-drench preventive programme of treatments for lambs, in which either zero, the first, third or fifth treatment was substituted with a different class of drug, were compared for the time to reach treatment failure (defined as efficacy
ISSN:0048-0169
1176-0710
1176-0710
DOI:10.1080/00480169.2009.36902