Taurine and cardiac disease: state of the art and perspectives1

Taurine is a nonessential amino acid that has received much attention. Two organs, the heart and the brain, are known to produce their own taurine, but in very limited quantities. It is for this reason that supplementation with this amino acid is necessary. Today, taurine is present in almost all en...

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Bibliographic Details
Published in:Canadian journal of physiology and pharmacology 2020, Vol.98 (2), p.67-73
Main Authors: Bkaily, Ghassan, Jazzar, Ashley, Normand, Alexandre, Simon, Yanick, Al-Khoury, Johny, Jacques, Danielle
Format: Article
Language:English
Subjects:
calcium
heart failure
hypertension
hypertrophie
hypertrophy
insuffisance cardiaque
sodium
taurine
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Summary:Taurine is a nonessential amino acid that has received much attention. Two organs, the heart and the brain, are known to produce their own taurine, but in very limited quantities. It is for this reason that supplementation with this amino acid is necessary. Today, taurine is present in almost all energy drinks. A very vast literature reported beneficial effects of taurine in hepatic dysfunction, gastrointestinal injury, kidney diseases, diabetes, and cardiovascular diseases. Most of its effects were attributed to its modulation of Ca 2+ homeostasis as well as to its antioxidant properties. In this review, we will focus on the current status of taurine modulation of the cardiovascular system and discuss future avenues for its use as a supplement therapy in a specific cardiovascular disease, namely hypertrophy, and heart failure.
ISSN:0008-4212
1205-7541
DOI:10.1139/cjpp-2019-0313