A Key Metabolic Regulator of Bone and Cartilage Health

Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also be obtained from food. In target tissues, such as the retina, heart, and skeletal musc...

Full description

Saved in:
Bibliographic Details
Published in:Endocrinology and metabolism (Seoul) 2022, 37(4), , pp.559-574
Main Authors: Pérez-Hernández, Elizabeth, Pastrana-Carballo, Jesús Javier, Gómez-Chávez, Fernando, Gupta, Ramesh C, Pérez-Hernández, Nury
Format: Article
Language:English
Subjects:
Animals
cartilage
Cartilage - metabolism
Humans
Muscle, Skeletal - metabolism
osteoarthritis
osteoblasts
osteoclasts
Osteogenesis
Osteoporosis
Review
taurine
Taurine - metabolism
내과학
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3
cites cdi_FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3
container_end_page 574
container_issue 4
container_start_page 559
container_title Endocrinology and metabolism (Seoul)
container_volume 37
creator Pérez-Hernández, Elizabeth
Pastrana-Carballo, Jesús Javier
Gómez-Chávez, Fernando
Gupta, Ramesh C
Pérez-Hernández, Nury
description Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also be obtained from food. In target tissues, such as the retina, heart, and skeletal muscle, it functions as an essential antioxidant, osmolyte, and antiapoptotic agent. Taurine is also involved in energy metabolism and calcium homeostasis. Taurine plays a considerable role in bone growth and development, and high-profile reports have demonstrated the importance of its metabolism for bone health. However, these reports have not been collated for more than 10 years. Therefore, this review focuses on taurine-bone interactions and covers recently discovered aspects of taurine's effects on osteoblastogenesis, osteoclastogenesis, bone structure, and bone pathologies (e.g., osteoporosis and fracture healing), with due attention to the taurine-cartilage relationship.
doi_str_mv 10.3803/EnM.2022.1443
format article
fullrecord <record><control><sourceid>proquest_nrf_k</sourceid><recordid>TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10034586</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_48f4a49ce5f0485aa220b33eb0a42cb7</doaj_id><sourcerecordid>2699960334</sourcerecordid><originalsourceid>FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3</originalsourceid><addsrcrecordid>eNpVkdFr2zAQh83YWEvXx70OP46B07N0lqWXQRa6NqxlUDrYmzhLp9StY3WyU-h_PyfpwqqXE9Kn7078suxjCTOpQZ6d99czAULMSkT5JjsWYGRRmVq_PezV76PsdBjuYVpaYynK99mRrIzUEvA4U_P8Bz_n1zxSE7vW5Te82nQ0xpTHkH-LPefU-3xBaWw7WnF-ydSNdx-yd4G6gU9f6kn26_v57eKyuPp5sVzMrwqHWo-FIIe1R2gwqFrVWLuSglMETlfee6o9N6Q8UhUqyQbYCOUZ6yZIAFZOnmRf9t4-BfvgWhup3dVVtA_Jzm9ul7YEkFhpNcHLPewj3dvH1K4pPe9e7A5iWtntN1zHFnVAQuO4CoC6IhICGim5AULhmnpyfd27HjfNmr3jfkzUvZK-vunbu2moJ2sQTQnlJPj8Ikjxz4aH0a7bwXHXUc9xM1ihjDEKpMQJLfaoS3EYEodDmxLsNmc75Wy3OdttzhP_6f_ZDvS_VOVfpuah5g</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2699960334</pqid></control><display><type>article</type><title>A Key Metabolic Regulator of Bone and Cartilage Health</title><source>PubMed (Medline)</source><creator>Pérez-Hernández, Elizabeth ; Pastrana-Carballo, Jesús Javier ; Gómez-Chávez, Fernando ; Gupta, Ramesh C ; Pérez-Hernández, Nury</creator><creatorcontrib>Pérez-Hernández, Elizabeth ; Pastrana-Carballo, Jesús Javier ; Gómez-Chávez, Fernando ; Gupta, Ramesh C ; Pérez-Hernández, Nury</creatorcontrib><description>Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also be obtained from food. In target tissues, such as the retina, heart, and skeletal muscle, it functions as an essential antioxidant, osmolyte, and antiapoptotic agent. Taurine is also involved in energy metabolism and calcium homeostasis. Taurine plays a considerable role in bone growth and development, and high-profile reports have demonstrated the importance of its metabolism for bone health. However, these reports have not been collated for more than 10 years. Therefore, this review focuses on taurine-bone interactions and covers recently discovered aspects of taurine's effects on osteoblastogenesis, osteoclastogenesis, bone structure, and bone pathologies (e.g., osteoporosis and fracture healing), with due attention to the taurine-cartilage relationship.</description><identifier>ISSN: 2093-596X</identifier><identifier>ISSN: 2093-5978</identifier><identifier>EISSN: 2093-5978</identifier><identifier>DOI: 10.3803/EnM.2022.1443</identifier><identifier>PMID: 35938304</identifier><language>eng</language><publisher>Korea (South): Korean Endocrine Society</publisher><subject>Animals ; cartilage ; Cartilage - metabolism ; Humans ; Muscle, Skeletal - metabolism ; osteoarthritis ; osteoblasts ; osteoclasts ; Osteogenesis ; Osteoporosis ; Review ; taurine ; Taurine - metabolism ; 내과학</subject><ispartof>Endocrinology and Metabolism, 2022, 37(4), , pp.559-574</ispartof><rights>Copyright © 2022 Korean Endocrine Society 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3</citedby><cites>FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3</cites><orcidid>0000-0001-5834-3960 ; 0000-0001-9806-6267 ; 0000-0001-8597-619X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449101/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449101/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35938304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002868365$$DAccess content in National Research Foundation of Korea (NRF)$$Hfree_for_read</backlink></links><search><creatorcontrib>Pérez-Hernández, Elizabeth</creatorcontrib><creatorcontrib>Pastrana-Carballo, Jesús Javier</creatorcontrib><creatorcontrib>Gómez-Chávez, Fernando</creatorcontrib><creatorcontrib>Gupta, Ramesh C</creatorcontrib><creatorcontrib>Pérez-Hernández, Nury</creatorcontrib><title>A Key Metabolic Regulator of Bone and Cartilage Health</title><title>Endocrinology and metabolism (Seoul)</title><addtitle>Endocrinol Metab (Seoul)</addtitle><description>Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also be obtained from food. In target tissues, such as the retina, heart, and skeletal muscle, it functions as an essential antioxidant, osmolyte, and antiapoptotic agent. Taurine is also involved in energy metabolism and calcium homeostasis. Taurine plays a considerable role in bone growth and development, and high-profile reports have demonstrated the importance of its metabolism for bone health. However, these reports have not been collated for more than 10 years. Therefore, this review focuses on taurine-bone interactions and covers recently discovered aspects of taurine's effects on osteoblastogenesis, osteoclastogenesis, bone structure, and bone pathologies (e.g., osteoporosis and fracture healing), with due attention to the taurine-cartilage relationship.</description><subject>Animals</subject><subject>cartilage</subject><subject>Cartilage - metabolism</subject><subject>Humans</subject><subject>Muscle, Skeletal - metabolism</subject><subject>osteoarthritis</subject><subject>osteoblasts</subject><subject>osteoclasts</subject><subject>Osteogenesis</subject><subject>Osteoporosis</subject><subject>Review</subject><subject>taurine</subject><subject>Taurine - metabolism</subject><subject>내과학</subject><issn>2093-596X</issn><issn>2093-5978</issn><issn>2093-5978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkdFr2zAQh83YWEvXx70OP46B07N0lqWXQRa6NqxlUDrYmzhLp9StY3WyU-h_PyfpwqqXE9Kn7078suxjCTOpQZ6d99czAULMSkT5JjsWYGRRmVq_PezV76PsdBjuYVpaYynK99mRrIzUEvA4U_P8Bz_n1zxSE7vW5Te82nQ0xpTHkH-LPefU-3xBaWw7WnF-ydSNdx-yd4G6gU9f6kn26_v57eKyuPp5sVzMrwqHWo-FIIe1R2gwqFrVWLuSglMETlfee6o9N6Q8UhUqyQbYCOUZ6yZIAFZOnmRf9t4-BfvgWhup3dVVtA_Jzm9ul7YEkFhpNcHLPewj3dvH1K4pPe9e7A5iWtntN1zHFnVAQuO4CoC6IhICGim5AULhmnpyfd27HjfNmr3jfkzUvZK-vunbu2moJ2sQTQnlJPj8Ikjxz4aH0a7bwXHXUc9xM1ihjDEKpMQJLfaoS3EYEodDmxLsNmc75Wy3OdttzhP_6f_ZDvS_VOVfpuah5g</recordid><startdate>20220801</startdate><enddate>20220801</enddate><creator>Pérez-Hernández, Elizabeth</creator><creator>Pastrana-Carballo, Jesús Javier</creator><creator>Gómez-Chávez, Fernando</creator><creator>Gupta, Ramesh C</creator><creator>Pérez-Hernández, Nury</creator><general>Korean Endocrine Society</general><general>대한내분비학회</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><scope>ACYCR</scope><orcidid>https://orcid.org/0000-0001-5834-3960</orcidid><orcidid>https://orcid.org/0000-0001-9806-6267</orcidid><orcidid>https://orcid.org/0000-0001-8597-619X</orcidid></search><sort><creationdate>20220801</creationdate><title>A Key Metabolic Regulator of Bone and Cartilage Health</title><author>Pérez-Hernández, Elizabeth ; Pastrana-Carballo, Jesús Javier ; Gómez-Chávez, Fernando ; Gupta, Ramesh C ; Pérez-Hernández, Nury</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animals</topic><topic>cartilage</topic><topic>Cartilage - metabolism</topic><topic>Humans</topic><topic>Muscle, Skeletal - metabolism</topic><topic>osteoarthritis</topic><topic>osteoblasts</topic><topic>osteoclasts</topic><topic>Osteogenesis</topic><topic>Osteoporosis</topic><topic>Review</topic><topic>taurine</topic><topic>Taurine - metabolism</topic><topic>내과학</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pérez-Hernández, Elizabeth</creatorcontrib><creatorcontrib>Pastrana-Carballo, Jesús Javier</creatorcontrib><creatorcontrib>Gómez-Chávez, Fernando</creatorcontrib><creatorcontrib>Gupta, Ramesh C</creatorcontrib><creatorcontrib>Pérez-Hernández, Nury</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><collection>Korean Citation Index (Open Access)</collection><jtitle>Endocrinology and metabolism (Seoul)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pérez-Hernández, Elizabeth</au><au>Pastrana-Carballo, Jesús Javier</au><au>Gómez-Chávez, Fernando</au><au>Gupta, Ramesh C</au><au>Pérez-Hernández, Nury</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Key Metabolic Regulator of Bone and Cartilage Health</atitle><jtitle>Endocrinology and metabolism (Seoul)</jtitle><addtitle>Endocrinol Metab (Seoul)</addtitle><date>2022-08-01</date><risdate>2022</risdate><volume>37</volume><issue>4</issue><spage>559</spage><epage>574</epage><pages>559-574</pages><issn>2093-596X</issn><issn>2093-5978</issn><eissn>2093-5978</eissn><abstract>Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also be obtained from food. In target tissues, such as the retina, heart, and skeletal muscle, it functions as an essential antioxidant, osmolyte, and antiapoptotic agent. Taurine is also involved in energy metabolism and calcium homeostasis. Taurine plays a considerable role in bone growth and development, and high-profile reports have demonstrated the importance of its metabolism for bone health. However, these reports have not been collated for more than 10 years. Therefore, this review focuses on taurine-bone interactions and covers recently discovered aspects of taurine's effects on osteoblastogenesis, osteoclastogenesis, bone structure, and bone pathologies (e.g., osteoporosis and fracture healing), with due attention to the taurine-cartilage relationship.</abstract><cop>Korea (South)</cop><pub>Korean Endocrine Society</pub><pmid>35938304</pmid><doi>10.3803/EnM.2022.1443</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0001-5834-3960</orcidid><orcidid>https://orcid.org/0000-0001-9806-6267</orcidid><orcidid>https://orcid.org/0000-0001-8597-619X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2093-596X
ispartof Endocrinology and Metabolism, 2022, 37(4), , pp.559-574
issn 2093-596X
2093-5978
2093-5978
language eng
recordid cdi_nrf_kci_oai_kci_go_kr_ARTI_10034586
source PubMed (Medline)
subjects Animals
cartilage
Cartilage - metabolism
Humans
Muscle, Skeletal - metabolism
osteoarthritis
osteoblasts
osteoclasts
Osteogenesis
Osteoporosis
Review
taurine
Taurine - metabolism
내과학
title A Key Metabolic Regulator of Bone and Cartilage Health
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T14%3A28%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_nrf_k&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Key%20Metabolic%20Regulator%20of%20Bone%20and%20Cartilage%20Health&rft.jtitle=Endocrinology%20and%20metabolism%20(Seoul)&rft.au=P%C3%A9rez-Hern%C3%A1ndez,%20Elizabeth&rft.date=2022-08-01&rft.volume=37&rft.issue=4&rft.spage=559&rft.epage=574&rft.pages=559-574&rft.issn=2093-596X&rft.eissn=2093-5978&rft_id=info:doi/10.3803/EnM.2022.1443&rft_dat=%3Cproquest_nrf_k%3E2699960334%3C/proquest_nrf_k%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c488t-2ac47d40b4f676747c1afc6a0c85ddda7deba6d4a5f53e90e926de47bf300e6c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2699960334&rft_id=info:pmid/35938304&rfr_iscdi=true