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Isolation, Identification and Characterization of a Antidementia Acetylcholinesterase Inhibitor-Producing Yarrowia lipolytica S-3

This report describes the isolation and identification of a potent acetylcholinesterase (AChE) inhibitor?producing yeasts. Of 731 species of yeast strain, the S-3 strain was selected as a potent producer of AChE inhibitor. The selected S-3 strain was investigated for its microbiological characterist...

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Bibliographic Details
Published in:Mycobiology 2012, 40(1), , pp.42-46
Main Authors: Kang, M.G., PaiChai University, Daejeon, Republic of Korea, Yoon, M.H., Chungnam National University, Daejeon, Republic of Korea, Choi, Y.J., National Research Council of Canada, Montreal, QC, Canada, Lee, J.S., PaiChai University, Daejeon, Republic of Korea
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Language:English
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Summary:This report describes the isolation and identification of a potent acetylcholinesterase (AChE) inhibitor?producing yeasts. Of 731 species of yeast strain, the S-3 strain was selected as a potent producer of AChE inhibitor. The selected S-3 strain was investigated for its microbiological characteristics. The S-3 strain was found to be short-oval yeast that did not form an ascospore. The strain formed a pseudomycelium and grew in yeast malt medium containing 50% glucose and 10% ethanol. Finally, the S-3 strain was identified by its physiological characteristics and 26S ribosomal DNA sequences as Yarrowia lipolytica S-3.
ISSN:1229-8093
2092-9323
DOI:10.5941/MYCO.2012.40.1.042