Patient-Reported Outcomes of Minimally Invasive versus Open Transforaminal Lumbar Interbody Fusion for Degenerative Lumbar Disc Disease: A Prospective Comparative Cohort Study

• Published in: Clinics in orthopedic surgery 2023, 15(2), , pp.257-264
• Main Authors: Jover-Mendiola, Antonio D, Lopez-Prats, Fernando A, Lizaur-Utrilla, Alejandro, Vizcaya-Moreno, Maria-Flores
• Format: Article
• Language: English
• Subjects: Cohort Studies; Humans; Intervertebral Disc Degeneration - surgery; Lumbar Vertebrae - surgery; Minimally Invasive Surgical Procedures - methods; Original; Pain; Patient Reported Outcome Measures; Prospective Studies; Quality of Life; Retrospective Studies; Spinal Fusion - methods; Treatment Outcome; 정형외과학
• ISSN: 2005-291X; 2005-4408
• DOI: 10.4055/cios22250

Comparative outcomes of minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and traditional open TLIF (O-TLIF) for degenerative lumbar disc disease have been poorly studied. The purpose of this study was to prospectively compare the outcomes between MI-TLIF and O-TLIF for patients with a degenerative disc disease, focusing on the functional capacity of patients in daily life. A prospective cohort study was performed, comparing 54 patients who underwent O-TLIF and 55 patients who underwent MI-TLIF with a follow-up of 4 years. Clinical evaluation was performed using the Oswestry Disability Index (ODI), 36-item short form survey (SF-36), and a visual analog scale for pain (VAS pain). Radiological evaluation was also performed. At the final follow-up, compared with O-TLIF, MI-TLIF was associated with significantly better intraoperative results, including similar operative time ( = 0.246), lower estimated blood loss ( = 0.001), and shorter hospital stay ( = 0.001). The final ODI score was significantly better in the MI-TLIF group ( = 0.031). The SF-36-physical ( = 0.023) and VAS pain ( = 0.024) scores were significantly better in the MI-TLIF group. There was no significant difference in the fusion rate ( = 0.747). The MI-TLIF technique is an effective and safe procedure for degenerative lumbar disc disease. Compared to traditional O-TLIF, MI-TLIF was associated with less disability and higher quality of life, with a low rate of intraoperative and postoperative complications.