한국인 조기 류마티스관절염 환자에서의 2010 ACR/EULAR 분류 기준의 유용성 및 한계

• Published in: Journal of rheumatic diseases 2012, 19(6), , pp.326-332
• Main Authors: 문수진, Su Jin Moon, 이창훈, Chang Hoon Lee, 김윤성, Yun Sung Kim, 박윤정, Yun Jung Park, 강귀영, Kwi Young Kang, 곽승기, Seung Ki Kwok, 김해림, Hae Rim Kim, 주지현, Ji Hyeon Ju, 김현숙, Hyun Sook Kim, 서영일, Young Il Seo, 최상태, Sang Tae Choi, 최진정, Jin Jung Choi, 김현아, Hyun Ah Kim, 김완욱, Wan Uk Kim, 윤종현, Chong Hyun Yoon, 홍연식, Yeon Sik Hong, 이명수, Myeung Su Lee, 이상헌, Sang Heon Lee, 송정수, Jung Soo Song, 박원, Won Park, 김호연, Ho Youn Kim, 박성환, Sung Hwan Park
• Format: Article
• Language: Korean
• Subjects: Criterion; Diagnosis; Rheumatoid arthritis; Seronegative; 내과학
• ISSN: 2093-940X; 2233-4718

The 2010 New American College of Rheumatology/ European League Against Rheumatism (ACR/EULAR) criteria for rheumatoid arthritis (RA) was raised to identify patients with early RA and replaced the 1987 ACR classification criteria. The aims of this study are to assess the availability of new classification criteria and to evaluate its Methods. A total of 408 patients with newly diagnosed RA were included from 13 secondary or tertiary hospitals in South Korea. The symptom duration was less than 12 months before the diagnosis of RA. RA was defined as either 1987 ACR classification criteria or new 2010 ACR/EULAR criteria. We compared the full details of both classification criteria. Results. The mean symptom duration was 5.1 months. The majority (76.2%) of the patients were female. Two hundred and seventy three patients (66.9%) fulfilled both of the 2010 and 1987 classification criteria. Forty-seven (14.7%) of the 320 patients fulfilling the 1987 criteria did not fulfill the new classification criteria. On the other hand, eighty-eight (24.4%) of the 361 patients fulfilling the 2010 ACR/EULAR classification criteria did not fulfill the 1987 ACR criteria. Thirty-six (55.4%) of the 65 patient with seronegative RA failed to meet the 2010 classification criteria. In case of seropositive RA (n=343), 85 additional patients (24.8%) could be diagnosed as RA using new classification criteria. The new 2010 ACR/EULAR classification criteria enable physicians to diagnose more patients with early RA via the help of serology. However, the sensitivity for the diagnosis of seronegative RA is projected to decrease.