The Use of Phentermine for Obesity in Psychiatric Patients With Antipsychotics

Objective Phentermine is a commonly used weight-loss agent in the United States, but there is a little information about the use of phentermine for patients with obesity taking antipsychotic medications.Methods We gathered 57 patients with obesity taking antipsychotic medications whose phentermine t...

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Bibliographic Details
Published in:Psychiatry investigation 2023, 20(9), , pp.799-807
Main Authors: Kim, Eunju, Rim, Daniel, Shin, Jeong-Hun, Wong, Denise, Kim, Dong Wook
Format: Article
Language:English
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정신과학
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Summary:Objective Phentermine is a commonly used weight-loss agent in the United States, but there is a little information about the use of phentermine for patients with obesity taking antipsychotic medications.Methods We gathered 57 patients with obesity taking antipsychotic medications whose phentermine treatment was simultaneous with or after any type of antipsychotic exposure and collected data of clinical information, initial/follow-up anthropometric variables, and adverse events (AEs) for the 6-month study period.Results In total, the mean body weight reduction (BWR) was 4.45 (7.04) kg, and the mean BWR percent (BWR%) was 3.92% (6.96%) at 6 months. Based on the response to phentermine, the patients were classified into two groups: the responder (n=25; BWR% ≥5%) and nonresponder (n=32; BWR%
ISSN:1738-3684
1976-3026
DOI:10.30773/pi.2023.0045