Prevalence of hypertension among antiretroviral therapy naïve patients in Lagos, Nigeria

Background The gains from successful antiretroviral therapy (ART) roll-out could be compromised by the increasing burden of non-communicable diseases, particularly cardiovascular diseases among people living with HIV (PLWH). Hypertension remains a significant contributor to cardiovascular diseases....

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Bibliographic Details
Published in:Clinical hypertension 2023, 29(0), , pp.29-29
Main Authors: Odubela, Oluwatosin, Odunukwe, Nkiruka, Peer, Nasheeta, Musa, Adesola Zaidat, Salako, Babatunde Lawal, Kengne, Andre Pascal
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Age
AIDS
Antiretroviral drugs
Antiviral agents
ART-naïve
Blood pressure
Body mass index
Care and treatment
Communicable diseases
Diabetes
Drug therapy
Education
Enrollments
Fertility clinics
Highly active antiretroviral therapy
HIV
HIV (Viruses)
Human immunodeficiency virus
Hypertension
Kidney diseases
Medical records
Medical research
Medical screening
Medicine, Experimental
Mortality
Nigeria
Patients
PLWH
Pregnant women
Prevalence
Prevalence studies (Epidemiology)
Regression analysis
Sociodemographics
Tuberculosis
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Summary:Background The gains from successful antiretroviral therapy (ART) roll-out could be compromised by the increasing burden of non-communicable diseases, particularly cardiovascular diseases among people living with HIV (PLWH). Hypertension remains a significant contributor to cardiovascular diseases. This study aims to determine the prevalence and determinants of hypertension among ART-naïve PLWH in a large ART clinic in Lagos, Nigeria. Materials and methods This study uses data collected from adult ART-naïve PLWH enrolled at an ART clinic over ten years. Participants aged 18 years and older, not pregnant, and not accessing care for post-exposure prophylaxis were included in the study. Hypertension was defined as systolic and diastolic blood pressure greater than or equal to 140 mmHg and 90 mmHg, respectively. Logistic regressions were used to investigate the factors associated with hypertension. Results Among the 10 426 participants included in the study, the majority were females (66%) and aged 25--49 years (84%). The crude prevalence of hypertension was 16.8% (95%CI 16.4 - 17.2) while the age and sex standardised prevalence rate was 21.9% (95%CI 20.7 - 23.2), with males (25.8%, 95%CI 23.5 - 28.0) having a higher burden compared with females (18.3%, 95%CI 17.0 - 19.6). Increasing age, male gender, overweight or obesity, co-morbid diabetes mellitus or renal disease, and CD4 count [greater than or equal to] 201 cells/[mu]L were significantly associated with prevalent hypertension. Conclusion There was a substantial burden of hypertension among ART-naïve PLWH, which was associated with the traditional risk factors of the condition. This highlights the need to integrate screening and care of hypertension into routine HIV management for optimal care of PLWH. Graphical Keywords: Hypertension, Prevalence, ART-naïve, PLWH, HIV, Nigeria
ISSN:2056-5909
1342-2154
2635-6325
2056-5909
DOI:10.1186/s40885-023-00253-6