Promising improvement in infected Wound Healing in Type two Diabetic rats by Combined effects of conditioned medium of human adipose-derived stem cells plus Photobiomodulation

We aimed to examine the accompanying and solo impacts of conditioned medium of human adipose-derived stem cells (h-ASC-COM) and photobiomodulation (PBM) on the maturation stage of an ischemic infected delayed-healing wound model (IIDHWM) of rats with type 2 diabetes (TIIDM). Outcomes of the wound cl...

Full description

Saved in:
Bibliographic Details
Published in:Laboratory animal research 2023, 39(4), , pp.356-370
Main Authors: Sohrabi, Kaysan, Ahmadi, Houssein, Amini, Abdollah, Ahrabi, Behnaz, Mostafavinia, Atarodalsadat, Omidi, Hamidreza, Mirzaei, Mansooreh, Fadaei Fathabady, Fatemeh, Fridoni, Mohammadjavad, Rahmannia, Maryam, Chien, Sufan, Bayat, Mohammad
Format: Article
Language:English
Subjects:
Conditioned medium
Diabetes mellitus
Diabetic foot ulcers
Human adipose-derived stem cell
Microbial flora
Photobiomodulation
수의학
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We aimed to examine the accompanying and solo impacts of conditioned medium of human adipose-derived stem cells (h-ASC-COM) and photobiomodulation (PBM) on the maturation stage of an ischemic infected delayed-healing wound model (IIDHWM) of rats with type 2 diabetes (TIIDM). Outcomes of the wound closure ratio (WCR) results, tensiometrical microbiological, and stereological assessment followed almost identical patterns. While the outcomes of h-ASC-COM + PBM, PBM only, and h-ASC-COM only regimes were significantly better for all evaluated methods than those of group 1(all, p 
ISSN:1738-6055
2233-7660
2233-7660
DOI:10.1186/s42826-023-00178-z