Biofoundries: Bridging Automation and Biomanufacturing in Synthetic Biology

Biofoundries represent advanced automation facilities pivotal for streamlining the Design-Build-Test-Learn (DBTL) paradigm in biomanufacturing and synthetic biology, suitable for both academic research and industrial applications. Nonetheless, establishing such a platform demands significant financi...

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Bibliographic Details
Published in:Biotechnology and bioprocess engineering 2023, 28(6), , pp.892-904
Main Authors: Lee, Dae-Hee, Kim, Haseong, Sung, Bong-Hyun, Cho, Byung Kwan, Lee, Seung-Goo
Format: Article
Language:English
Subjects:
Automation
Bioengineering
Biology
Biotechnology
Chemistry
Chemistry and Materials Science
Collaboration
Design
Industrial and Production Engineering
Industrial applications
Innovations
Review Paper
Software
생물공학
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Summary:Biofoundries represent advanced automation facilities pivotal for streamlining the Design-Build-Test-Learn (DBTL) paradigm in biomanufacturing and synthetic biology, suitable for both academic research and industrial applications. Nonetheless, establishing such a platform demands significant financial and temporal resources while maintaining a forward-looking perspective on automation, equipment compatibility, and operational efficiency. Despite its challenges, international collaborations between global biofoundries may offer solutions. The automated DBTL framework in biofoundries has transformed the production of bioproducts using engineered microbes. As the field advances, biofoundries are essential for streamlining and standardizing biotechnological processes, addressing efficiency, cost, and consistency challenges.
ISSN:1226-8372
1976-3816
DOI:10.1007/s12257-023-0226-x