Antifungal Activity-Guided Analysis of Actinostemma lobatum Extracts through Serial Sub-fractions

Plants are treasure trove of novel compounds that have potential for antifungal chemicals and drugs. In our previous study, we had screened plant extracts obtained from more than eight hundred plant materials collected in Korea, and found that butanol fraction of the Actinostemma lobatum were most p...

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Bibliographic Details
Published in:The plant pathology journal 2024, 40(1), , pp.218-224
Main Authors: Choi, Seonwoo, Lee, Song Hee, Hwang, Byeong Su, Oh, Young Taek, Jeon, Junhyun
Format: Article
Language:English
Subjects:
antifungal activity
biological activity-guided sub-fractionation
plant extracts
농학
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Summary:Plants are treasure trove of novel compounds that have potential for antifungal chemicals and drugs. In our previous study, we had screened plant extracts obtained from more than eight hundred plant materials collected in Korea, and found that butanol fraction of the Actinostemma lobatum were most potent in suppressing growth of diverse fungal pathogens of plants. Here in this study, we describe further analysis of the butanol fraction, and summarize the results of subsequent antifungal activity test for the sub-fractions against a selected set of plant pathogenic fungi. This line of analyses allowed us to identify the sub-fractions that could account for a significant proportion of observed antifungal activity of initial butanol fraction from A. lobatum. Further analysis of these sub-fractions and determination of structure would provide the shortlist for novel compounds that can be a lead to new agrochemicals.
ISSN:1598-2254
2093-9280
2093-9280
DOI:10.5423/PPJ.NT.11.2023.0152