[18F]FDOPA PET/CT in Solid Pseudopapillary Tumor of the Pancreas: a Recurred Tumor Mimicking Splenosis

Solid pseudopapillary tumor (SPT) of the pancreas is a neoplasm with low malignant potential. It is often challenging to diagnose SPT due to its nonspecific clinical and radiological features, and [ 18 F]FDOPA is effective in diagnosing SPT, particularly in differentiating SPT from benign conditions...

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Published in:Nuclear medicine and molecular imaging 2024, 58(2), , pp.81-85
Main Authors: Gil, Joonhyung, Suh, Minseok, Choi, Hongyoon, Paeng, Jin Chul, Cheon, Gi Jeong, Kang, Keon Wook
Format: Article
Language:English
Subjects:
Cardiology
Case Report
Computed tomography
Erythrocytes
Fluorine isotopes
Imaging
Medicine
Medicine & Public Health
Nodules
Nuclear Medicine
Oncology
Orthopedics
Pancreas
Radiology
Tumors
방사선과학
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Summary:Solid pseudopapillary tumor (SPT) of the pancreas is a neoplasm with low malignant potential. It is often challenging to diagnose SPT due to its nonspecific clinical and radiological features, and [ 18 F]FDOPA is effective in diagnosing SPT, particularly in differentiating SPT from benign conditions such as splenosis. A 55-year-old woman underwent distal pancreatectomy and splenectomy for histologically confirmed SPT. She was also initially diagnosed with splenosis. During follow-up, sizes of multiple nodular lesions were increased, raising the possibility of peritoneal seeding of SPT. For diagnosis, a spleen scan and SPECT/CT were performed using 99m Tc-labeled damaged red blood cells, which showed no uptake in the peritoneal nodules. Subsequent [ 18 F]FDOPA PET/CT revealed [ 18 F]FDOPA-avidity of the nodules. The patient underwent tumor resection surgery, and the nodules were pathologically confirmed as SPT.
ISSN:1869-3474
1869-3482
DOI:10.1007/s13139-023-00826-1