Trends and all-cause mortality associated with multimorbidity of noncommunicable diseases among adults in the United States, 1999-2018: a retrospective cohort study

• Published in: Epidemiology and health 2023, 45(0), , pp.023-023
• Main Authors: Sun Mengzi, Wang Ling, Wang Xuhan, Tong Li, Jin Lina, Li Bo
• Format: Article
• Language: English
• Subjects: 예방의학
• ISSN: 2092-7193
• DOI: 10.4178/epih.e2023023

Objectives: Multimorbidity of noncommunicable diseases (NCDs) has brought enormous challenges to public health, becoming a major medical burden. However, the patterns, temporal trends, and all-cause mortality associated with NCD multimorbidity over time have not been well described in the United States.Methods: All adult participants were sourced from nationally representative data from the National Health and Nutrition Examination Survey. In total, 55,081 participants were included in trend analysis, and 38,977 participants were included in Cox regression. Results: The 5 NCDs with the largest increases over the study period were diabetes, osteoporosis, obesity, liver conditions, and cancer. The estimated prevalence of multimorbidity increased with age, especially for middle-aged participants with 5 or more NCDs; in general, the prevalence of NCD multimorbidity was higher among women than men. Participants with 5 or more NCDs were at 4.49 times the risk of all-cause mortality of participants without any diseases. Significant interactions were found between multimorbidity and age group (P for interaction