Fast fluorescent blood sugar sensing using phenylboronic acid functionalized N, S-doped carbon dots

A phenylboric acid functionalized carbon dot (2-FPBA-CD) for rapid fluorescent sensing of glucose in blood was synthesized by simply mixing N, S-doped carbon dots (CDs) with phenylboric acid at room temperature. At pH 7.4, the response of 2-FPBA-CD to glucose could reach equilibrium in a very short...

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Bibliographic Details
Published in:Carbon Letters 2024, 34(5), , pp.1355-1366
Main Authors: Wang, Xiaoge, Fan, Xiangze, Zhang, Bowen, Zhan, Mengke, Zhu, Jinhua, Hu, Weiping, Liu, Xiuhua
Format: Article
Language:English
Subjects:
Amino acids
Blood
Carbon
Carbon dots
Characterization and Evaluation of Materials
Chemistry and Materials Science
Chemoreception
Fluorescence
Glucose
Materials Engineering
Materials Science
Morphology
Nanoparticles
Nanotechnology
Original Article
Quantum dots
Raw materials
Room temperature
Temperature
자연과학일반
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Summary:A phenylboric acid functionalized carbon dot (2-FPBA-CD) for rapid fluorescent sensing of glucose in blood was synthesized by simply mixing N, S-doped carbon dots (CDs) with phenylboric acid at room temperature. At pH 7.4, the response of 2-FPBA-CD to glucose could reach equilibrium in a very short time (10 min), with a wide responsive linear range of 19.70 µM to 2.54 mM, which can be applied to the detection of glucose in serum. The mechanism studies showed that the layered carbon film of 2-FPBA-CD aggregated after adding glucose, thereby leading to the fluorescence quenching of 2-FPBA-CD. Graphical abstract
ISSN:1976-4251
2233-4998
DOI:10.1007/s42823-024-00696-3