Does Lymphocytic Colitis Always Present with Normal Endoscopic Findings?

Background/Aims: Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, sev-eral cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, c...

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Bibliographic Details
Published in:Gut and liver 2015, 9(2), , pp.197-201
Main Authors: Park, Hye Sun, Han, Dong Soo, Ro, Young Ouk, Eun, Chang Soo, Yoo, Kyo Sang
Format: Article
Language:English
Subjects:
Adult
Aged
Colitis, Collagenous - pathology
Colitis, Lymphocytic - complications
Colitis, Lymphocytic - pathology
Colon - pathology
Colonoscopy
Diagnosis, Differential
Diarrhea - etiology
Exudative
Female
Hemorrhage
Humans
Hypervascularity
Intestinal Mucosa - pathology
Lymphocytic colitis
Male
Middle Aged
Original
Retrospective Studies
내과학
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Summary:Background/Aims: Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, sev-eral cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, clini-cal, and histopathologic features of LC with MLs. Methods: A total of 14 patients with LC who were diagnosed between 2005 and 2010 were enrolled in the study. Endoscopic, clini-cal, and histopathologic findings were compared retrospec-tively according to the presence or absence of MLs. Results: MLs were observed in seven of the 14 LC cases. Six of the MLs exhibited hypervascularity, three exhibited exudative bleeding and one exhibited edema. The patients with MLs had more severe diarrhea and were taking aspirin or pro-ton pump inhibitors. More intraepithelial lymphocytes were observed during histologic examination in the patients with MLs compared to the patients without MLs, although this difference was not significant. The numbers of mononuclear cells and neutrophils in the lamina propria were independent of the presence or absence of MLs. Conclusions: LC does not always present with normal endoscopic findings. Hyper-vascularity and exudative bleeding are frequent endoscopic findings in patients with MLs. (Gut Liver, 2015;9:197-201)
ISSN:1976-2283
2005-1212
DOI:10.5009/gnl13373