Symptom characteristics and psychosomatic profiles in different spectrum of gastroesophageal reflux disease

Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics a...

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Bibliographic Details
Published in:Gut and liver 2014, 8(2), , pp.165-169
Main Authors: Lim, Chul-Hyun, Choi, Myung-Gyu, Baeg, Myong Ki, Moon, Sung Jin, Kim, Jin Su, Cho, Yu Kyung, Park, Jae Myung, Lee, In Seok, Kim, Sang Woo, Choi, Kyu Yong
Format: Article
Language:English
Subjects:
Adult
Aged
demographic characteristics
Depressive Disorder - etiology
Esophageal pH Monitoring
esophageal reflux monitoring
Esophagitis, Peptic - complications
Esophagitis, Peptic - diagnosis
Female
gastroesophageal reflux
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - diagnosis
Gastroesophageal Reflux - psychology
Humans
Irritable Bowel Syndrome - complications
Male
Middle Aged
Original
Psychophysiologic Disorders - etiology
psychosomatic factor
Retrospective Studies
Surveys and Questionnaires
symptom characteristic
Young Adult
내과학
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Summary:Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics and reflux symptom patterns among patients with various spectrum of GERD. Patients having weekly heartburn or acid regurgitation were classified into four pathophysiological subgroups according to endoscopy and pH monitoring: reflux esophagitis (RE), endoscopy-negative reflux disease with pathological reflux (PR+), hypersensitive esophagus (HE), and normal acid exposure with negative symptom association (pH-). A total of 195 patients were enrolled. The numbers of patients in the subgroups were: RE, 39.0%; PR+, 20.0%; HE, 10.3%; and pH-, 30.8%. Grossly, reflux symptom patterns and relieving/exacerbating factors did not differ between subgroups. Prevalence of extraesophageal syndrome was higher in patients with PR+ than in other groups. Overlapping functional dyspepsia was common in all groups. The SCL-90-R depression score was higher in PR+ patients than in RE patients (p
ISSN:1976-2283
2005-1212
DOI:10.5009/gnl.2014.8.2.165