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Symptom characteristics and psychosomatic profiles in different spectrum of gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics a...
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| Published in: | Gut and liver 2014, 8(2), , pp.165-169 |
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| cited_by | cdi_FETCH-LOGICAL-c496t-1afca12fadfdee3ac4312bece20db987374f3373581c3525a9c9d635fdcd41093 |
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| container_end_page | 169 |
| container_issue | 2 |
| container_start_page | 165 |
| container_title | Gut and liver |
| container_volume | 8 |
| creator | Lim, Chul-Hyun Choi, Myung-Gyu Baeg, Myong Ki Moon, Sung Jin Kim, Jin Su Cho, Yu Kyung Park, Jae Myung Lee, In Seok Kim, Sang Woo Choi, Kyu Yong |
| description | Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics and reflux symptom patterns among patients with various spectrum of GERD.
Patients having weekly heartburn or acid regurgitation were classified into four pathophysiological subgroups according to endoscopy and pH monitoring: reflux esophagitis (RE), endoscopy-negative reflux disease with pathological reflux (PR+), hypersensitive esophagus (HE), and normal acid exposure with negative symptom association (pH-).
A total of 195 patients were enrolled. The numbers of patients in the subgroups were: RE, 39.0%; PR+, 20.0%; HE, 10.3%; and pH-, 30.8%. Grossly, reflux symptom patterns and relieving/exacerbating factors did not differ between subgroups. Prevalence of extraesophageal syndrome was higher in patients with PR+ than in other groups. Overlapping functional dyspepsia was common in all groups. The SCL-90-R depression score was higher in PR+ patients than in RE patients (p |
| doi_str_mv | 10.5009/gnl.2014.8.2.165 |
| format | article |
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Patients having weekly heartburn or acid regurgitation were classified into four pathophysiological subgroups according to endoscopy and pH monitoring: reflux esophagitis (RE), endoscopy-negative reflux disease with pathological reflux (PR+), hypersensitive esophagus (HE), and normal acid exposure with negative symptom association (pH-).
A total of 195 patients were enrolled. The numbers of patients in the subgroups were: RE, 39.0%; PR+, 20.0%; HE, 10.3%; and pH-, 30.8%. Grossly, reflux symptom patterns and relieving/exacerbating factors did not differ between subgroups. Prevalence of extraesophageal syndrome was higher in patients with PR+ than in other groups. Overlapping functional dyspepsia was common in all groups. The SCL-90-R depression score was higher in PR+ patients than in RE patients (p<0.05).
Demographic characteristics and reflux symptom patterns cannot differentiate pH- group from GERD subtypes. Esophageal pH monitoring could be considered for the initial evaluation of GERD in the tertiary referral setting.</description><identifier>ISSN: 1976-2283</identifier><identifier>EISSN: 2005-1212</identifier><identifier>DOI: 10.5009/gnl.2014.8.2.165</identifier><identifier>PMID: 24672658</identifier><language>eng</language><publisher>Korea (South): The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer</publisher><subject>Adult ; Aged ; demographic characteristics ; Depressive Disorder - etiology ; Esophageal pH Monitoring ; esophageal reflux monitoring ; Esophagitis, Peptic - complications ; Esophagitis, Peptic - diagnosis ; Female ; gastroesophageal reflux ; Gastroesophageal Reflux - complications ; Gastroesophageal Reflux - diagnosis ; Gastroesophageal Reflux - psychology ; Humans ; Irritable Bowel Syndrome - complications ; Male ; Middle Aged ; Original ; Psychophysiologic Disorders - etiology ; psychosomatic factor ; Retrospective Studies ; Surveys and Questionnaires ; symptom characteristic ; Young Adult ; 내과학</subject><ispartof>Gut and Liver, 2014, 8(2), , pp.165-169</ispartof><rights>Copyright © 2014 by the Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c496t-1afca12fadfdee3ac4312bece20db987374f3373581c3525a9c9d635fdcd41093</citedby><cites>FETCH-LOGICAL-c496t-1afca12fadfdee3ac4312bece20db987374f3373581c3525a9c9d635fdcd41093</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964267/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964267/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24672658$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001858274$$DAccess content in National Research Foundation of Korea (NRF)$$Hfree_for_read</backlink></links><search><creatorcontrib>Lim, Chul-Hyun</creatorcontrib><creatorcontrib>Choi, Myung-Gyu</creatorcontrib><creatorcontrib>Baeg, Myong Ki</creatorcontrib><creatorcontrib>Moon, Sung Jin</creatorcontrib><creatorcontrib>Kim, Jin Su</creatorcontrib><creatorcontrib>Cho, Yu Kyung</creatorcontrib><creatorcontrib>Park, Jae Myung</creatorcontrib><creatorcontrib>Lee, In Seok</creatorcontrib><creatorcontrib>Kim, Sang Woo</creatorcontrib><creatorcontrib>Choi, Kyu Yong</creatorcontrib><title>Symptom characteristics and psychosomatic profiles in different spectrum of gastroesophageal reflux disease</title><title>Gut and liver</title><addtitle>Gut Liver</addtitle><description>Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics and reflux symptom patterns among patients with various spectrum of GERD.
Patients having weekly heartburn or acid regurgitation were classified into four pathophysiological subgroups according to endoscopy and pH monitoring: reflux esophagitis (RE), endoscopy-negative reflux disease with pathological reflux (PR+), hypersensitive esophagus (HE), and normal acid exposure with negative symptom association (pH-).
A total of 195 patients were enrolled. The numbers of patients in the subgroups were: RE, 39.0%; PR+, 20.0%; HE, 10.3%; and pH-, 30.8%. Grossly, reflux symptom patterns and relieving/exacerbating factors did not differ between subgroups. Prevalence of extraesophageal syndrome was higher in patients with PR+ than in other groups. Overlapping functional dyspepsia was common in all groups. The SCL-90-R depression score was higher in PR+ patients than in RE patients (p<0.05).
Demographic characteristics and reflux symptom patterns cannot differentiate pH- group from GERD subtypes. Esophageal pH monitoring could be considered for the initial evaluation of GERD in the tertiary referral setting.</description><subject>Adult</subject><subject>Aged</subject><subject>demographic characteristics</subject><subject>Depressive Disorder - etiology</subject><subject>Esophageal pH Monitoring</subject><subject>esophageal reflux monitoring</subject><subject>Esophagitis, Peptic - complications</subject><subject>Esophagitis, Peptic - diagnosis</subject><subject>Female</subject><subject>gastroesophageal reflux</subject><subject>Gastroesophageal Reflux - complications</subject><subject>Gastroesophageal Reflux - diagnosis</subject><subject>Gastroesophageal Reflux - psychology</subject><subject>Humans</subject><subject>Irritable Bowel Syndrome - complications</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original</subject><subject>Psychophysiologic Disorders - etiology</subject><subject>psychosomatic factor</subject><subject>Retrospective Studies</subject><subject>Surveys and Questionnaires</subject><subject>symptom characteristic</subject><subject>Young Adult</subject><subject>내과학</subject><issn>1976-2283</issn><issn>2005-1212</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVks1v1DAQxSMEotvCnRPKEQ67-CO24wtSVQFdqRISlLM1scfZdJM42EnF_ve4u6Wip5HG7_08M3pF8Y6SjSBEf2rHfsMIrTb1hm2oFC-KFSNErCmj7GWxolrJNWM1PyvOU7ojRFKmxOvijFVSMSnqVbH_eRimOQyl3UEEO2Ps0tzZVMLoyikd7C6kMEBulVMMvusxld1Yus57jDjOZZrQznEZyuDLFtIcA6Yw7aBF6MuIvl_-ZHVCSPimeOWhT_j2sV4Uv75-ub26Xt98_7a9urxZ20rLeU3BW6DMg_MOkYOtOGUNWmTENbpWXFWec8VFTS0XTIC22kkuvLOuokTzi-LjiTtGb_a2MwG6Y22D2Udz-eN2aygRlSY0a7cnrQtwZ6bYDRAPR8OxEWJrIObtezSqlo1ygnHJbQUKIJ-XSdVowSVpOGbW5xNrWpoBnc3nidA_gz5_GbtdnunecC2rTMqAD4-AGH4vmGYzdMli38OIYUmGCkq5VrUSWUpOUhtDSvnOT99QYh6yYXI2zEM2TG2YydnIlvf_j_dk-BcG_hfx2rip</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Lim, Chul-Hyun</creator><creator>Choi, Myung-Gyu</creator><creator>Baeg, Myong Ki</creator><creator>Moon, Sung Jin</creator><creator>Kim, Jin Su</creator><creator>Cho, Yu Kyung</creator><creator>Park, Jae Myung</creator><creator>Lee, In Seok</creator><creator>Kim, Sang Woo</creator><creator>Choi, Kyu Yong</creator><general>The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer</general><general>Gastroenterology Council for Gut and Liver</general><general>거트앤리버 소화기연관학회협의회</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><scope>ACYCR</scope></search><sort><creationdate>20140301</creationdate><title>Symptom characteristics and psychosomatic profiles in different spectrum of gastroesophageal reflux disease</title><author>Lim, Chul-Hyun ; Choi, Myung-Gyu ; Baeg, Myong Ki ; Moon, Sung Jin ; Kim, Jin Su ; Cho, Yu Kyung ; Park, Jae Myung ; Lee, In Seok ; Kim, Sang Woo ; Choi, Kyu Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c496t-1afca12fadfdee3ac4312bece20db987374f3373581c3525a9c9d635fdcd41093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Aged</topic><topic>demographic characteristics</topic><topic>Depressive Disorder - etiology</topic><topic>Esophageal pH Monitoring</topic><topic>esophageal reflux monitoring</topic><topic>Esophagitis, Peptic - complications</topic><topic>Esophagitis, Peptic - diagnosis</topic><topic>Female</topic><topic>gastroesophageal reflux</topic><topic>Gastroesophageal Reflux - complications</topic><topic>Gastroesophageal Reflux - diagnosis</topic><topic>Gastroesophageal Reflux - psychology</topic><topic>Humans</topic><topic>Irritable Bowel Syndrome - complications</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original</topic><topic>Psychophysiologic Disorders - etiology</topic><topic>psychosomatic factor</topic><topic>Retrospective Studies</topic><topic>Surveys and Questionnaires</topic><topic>symptom characteristic</topic><topic>Young Adult</topic><topic>내과학</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lim, Chul-Hyun</creatorcontrib><creatorcontrib>Choi, Myung-Gyu</creatorcontrib><creatorcontrib>Baeg, Myong Ki</creatorcontrib><creatorcontrib>Moon, Sung Jin</creatorcontrib><creatorcontrib>Kim, Jin Su</creatorcontrib><creatorcontrib>Cho, Yu Kyung</creatorcontrib><creatorcontrib>Park, Jae Myung</creatorcontrib><creatorcontrib>Lee, In Seok</creatorcontrib><creatorcontrib>Kim, Sang Woo</creatorcontrib><creatorcontrib>Choi, Kyu Yong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><collection>Korean Citation Index</collection><jtitle>Gut and liver</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lim, Chul-Hyun</au><au>Choi, Myung-Gyu</au><au>Baeg, Myong Ki</au><au>Moon, Sung Jin</au><au>Kim, Jin Su</au><au>Cho, Yu Kyung</au><au>Park, Jae Myung</au><au>Lee, In Seok</au><au>Kim, Sang Woo</au><au>Choi, Kyu Yong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Symptom characteristics and psychosomatic profiles in different spectrum of gastroesophageal reflux disease</atitle><jtitle>Gut and liver</jtitle><addtitle>Gut Liver</addtitle><date>2014-03-01</date><risdate>2014</risdate><volume>8</volume><issue>2</issue><spage>165</spage><epage>169</epage><pages>165-169</pages><issn>1976-2283</issn><eissn>2005-1212</eissn><abstract>Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics and reflux symptom patterns among patients with various spectrum of GERD.
Patients having weekly heartburn or acid regurgitation were classified into four pathophysiological subgroups according to endoscopy and pH monitoring: reflux esophagitis (RE), endoscopy-negative reflux disease with pathological reflux (PR+), hypersensitive esophagus (HE), and normal acid exposure with negative symptom association (pH-).
A total of 195 patients were enrolled. The numbers of patients in the subgroups were: RE, 39.0%; PR+, 20.0%; HE, 10.3%; and pH-, 30.8%. Grossly, reflux symptom patterns and relieving/exacerbating factors did not differ between subgroups. Prevalence of extraesophageal syndrome was higher in patients with PR+ than in other groups. Overlapping functional dyspepsia was common in all groups. The SCL-90-R depression score was higher in PR+ patients than in RE patients (p<0.05).
Demographic characteristics and reflux symptom patterns cannot differentiate pH- group from GERD subtypes. Esophageal pH monitoring could be considered for the initial evaluation of GERD in the tertiary referral setting.</abstract><cop>Korea (South)</cop><pub>The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer</pub><pmid>24672658</pmid><doi>10.5009/gnl.2014.8.2.165</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1976-2283 |
| ispartof | Gut and Liver, 2014, 8(2), , pp.165-169 |
| issn | 1976-2283 2005-1212 |
| language | eng |
| recordid | cdi_nrf_kci_oai_kci_go_kr_ARTI_1054901 |
| source | PubMed Central |
| subjects | Adult Aged demographic characteristics Depressive Disorder - etiology Esophageal pH Monitoring esophageal reflux monitoring Esophagitis, Peptic - complications Esophagitis, Peptic - diagnosis Female gastroesophageal reflux Gastroesophageal Reflux - complications Gastroesophageal Reflux - diagnosis Gastroesophageal Reflux - psychology Humans Irritable Bowel Syndrome - complications Male Middle Aged Original Psychophysiologic Disorders - etiology psychosomatic factor Retrospective Studies Surveys and Questionnaires symptom characteristic Young Adult 내과학 |
| title | Symptom characteristics and psychosomatic profiles in different spectrum of gastroesophageal reflux disease |
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