The Frequency and Risk Factors of Colorectal Adenoma in Health-Check-up Subjects in South Korea: Relationship to Abdominal Obesity and Age

• Published in: Gut and liver 2010, 4(1), , pp.36-42
• Main Authors: Kim, Ki-Seong, Moon, Hong Ju, Choi, Chang Hwan, Baek, Eun Kyung, Lee, Seung Young, Cha, Bong Ki, Lee, Hyun Woong, Kim, Hyung Joon, Do, Jae Hyuk, Chang, Sae Kyung
• Format: Article
• Language: English
• Subjects: abdominal obesity; colorectal adenoma; Original; 내과학
• ISSN: 1976-2283; 2005-1212
• DOI: 10.5009/gnl.2010.4.1.36

Obesity is associated with the risk of colorectal cancer. However, there is a lack of information about the relationship between obesity and colorectal adenoma. We investigated whether general and abdominal obesity are risk factors for colorectal adenoma. Subjects who received health check-ups, including colonoscopy, from April 2006 to September 2007 in Chung-Ang University Hospital were included (n=1,316). The frequency and characteristics of colorectal adenomas were analyzed according to demographic features, past history, blood tests, body mass index, and components of metabolic syndrome. Abdominal obesity was defined as a waist circumference of >/=80 cm in women and >/=90 cm in men. The sex ratio of the subjects was 1.9:1 (male:female) and their age was 47.7+/-10.0 years (mean+/-SD). In univariate analysis, abdominal obesity was significantly associated with the frequency of colorectal adenoma (26.5% "yes" vs 16.9% "no"; p/=100 mg/dL) or fatty liver (p/=60 years; OR, 6.7; 95% CI, 3.5-12.5), and abdominal obesity (OR, 1.5; 95% CI, 1.0-2.2) were independent risk factors for colorectal adenoma (p