Utility of eosinophil granule proteins in management of pediatric chronic cough

· Pediatric chronic cough often involves eosinophilic inflammation; however, objective measurements are not routinely used in treatment decisions. · Accurate biomarkers of eosinophil activity, such as eosinophil-derived neurotoxin (EDN) and cationic proteins (ECP), should be used. EDN, which overcom...

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Bibliographic Details
Published in:Clinical and experimental pediatrics 2024, 67(10), , pp.519-520
Main Author: Kim, Chang-Keun
Format: Article
Language:English
Subjects:
소아과학
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Summary:· Pediatric chronic cough often involves eosinophilic inflammation; however, objective measurements are not routinely used in treatment decisions. · Accurate biomarkers of eosinophil activity, such as eosinophil-derived neurotoxin (EDN) and cationic proteins (ECP), should be used. EDN, which overcomes the shortcomings of ECP, recently received approval for use in Korean healthcare settings. · EDN and ECP can play a role in treatment period and drug selection decisions. KCI Citation Count: 0
ISSN:2713-4148
2713-4148
DOI:10.3345/cep.2023.01431